Profiling and Structure Activity Relationships
Cellular profiling assays: For any compound, we offer two high-throughput cytotoxicity/apoptosis readouts in three standard cell lines. We also have developed a high content cellular growth and survival imaging assay can that can be used to screen, classify and/or, prioritize drugs or compounds. It may also help to accelerate mechanism of action studies.
Structure Activity Relationships by Inventory: For any validated hit compound we can search a database of 5 million commercially available compounds in order to find analogs for structure activity studies. We can also pick the most likely to be soluble, and cell permeable.