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Density does it: Fibrinogen concentration controls clot formation

When blood clots over a wound, the resulting scab is the product of an intricate molecular dance between cell fragments called platelets in the blood and the glycoprotein fibrinogen. Fibrinogen sticks to the wound's surface, and when platelets float by the fibrinogen it turns on a receptor on the...

To recognize their friends, mice use their amygdalas

Even those who can’t remember names can usually recall faces. New research from Rockefeller University suggests that a simple brain chemical, a neuropeptide called oxytocin, is a reason. Social recognition is an important part of normal life for animals of every species. “Remembering an individ...

Hepatitis C virus blocks 'superinfection'

There’s infection and then there’s superinfection – when a cell already infected by a virus gets a second viral infection. But some viruses don’t like to share their cells. New research from Rockefeller University shows that the hepatitis C virus, which infects cells in the liver and can cau...

Understanding ubiquitylation: Researchers identify a process that enables access to genes

It turns out there’s more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought. Access to a gene requires a host of proteins to work in tandem to pry open DNA’s protective chrom...

New glimpse into early brain development shows how nerve cells move into position

Tucked into the lower, rear portion of the brain, the cerebellum plays key roles in motor learning, motor memory and sensory perception. It’s also where the majority of metastatic childhood brain tumors are located. Yet scientists still know very little about its early growth. Now, new research h...

Immune response to cancer stem cells may dictate cancer's course

Although stem cells hold incredible promise in the fight against certain diseases, in cancer they’re anything but helpful. In fact, mounting evidence is showing that a tumor’s growth and spread may depend on “cancer stem cells,” which comprise only a very small subset of the tumor. Now, a ne...

Announcements

New support group available. The Employee Assistance Program Consortium is offering a support group this spring for parents of infants and toddlers. The group will meet on consecutive Mondays beginning April 2; all sessions will meet from 12 to 1 p.m. at New York-Presbyterian Hospital. EAPC couns...

Fundraising campaign passes $400 million mark

by ZACH VEILLEUX After a record-setting year ending in June 2006, new gifts recorded in the past few months have pushed Rockefeller’s seven-year Campaign for Collaborative Science closer to its goal of bringing in $500 million to pay for initiatives outlined in the strategic plan. At present, $41...

Five new trustees elected to Board

by TALLEY HENNING BROWN The Rockefeller Board of Trustees elected five new members in 2006, increasing the total number of trustees and trustees emeriti to 54. The new constituents include one lawyer, two chartered financial analysts, a private equity professional and — slightly unusual for Rocke...

Funding our laboratories

The Rockefeller University is unusual — in fact almost unique amongst U.S. universities — in providing ongoing significant direct support to individual laboratories as part of its routine annual operating budget. Much of this direct support is quantified by the application of a formula. Over the...