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Kety protein for Hepatitis C entry identified

For as many as 200 million people worldwide infected with hepatitis C, a leading cause of chronic liver disease, treatment options are only partially effective. But new research by Rockefeller University scientists points to a potential new target for better drugs: a key protein that resides in h...

Sex hormone signaling helps burn calories

Any dieter can tell you: Body weight is a function of how much food you eat and how much energy you use. The trick to maintaining a healthy weight lies in regulating the balance. Now new research from Rockefeller University suggests that brain cell receptors linked to sex hormones may play a role...

DNA barcoding uncovers likely new species of birds and bats

In the first effort to ever “barcode” species on a continental scale, scientists have completed a pilot study of U.S. and Canadian birds that suggests that 15 new genetically distant species have been overlooked in centuries of bird studies. The research validates DNA “barcoding” as an effic...

Rockefelller, with 42 other institutions, to create regional academic job bank

A new partnership among 43 leading higher education institutions in the region, including Rockefeller University, announced its first product today: a comprehensive job bank of academic opportunities in the greater New York City and southern Connecticut region. The partnership, known as the Metro...

Single gene may defend bacteria from antibiotics and infection

Bacteria have two major enemies: antibiotic drugs and bacteriophage viruses, which infect and kill them. The two disparate threats may have something in common. New research from Rockefeller University has found that certain bacteria have gained a gene that protects them from both toxic drugs and...

An ancient retrovirus is resurrected

Retroviruses have been around longer than humanity itself. In fact, the best-known family member, HIV, is a relative youngster, with its first known human infections occurring sometime in the mid-20th century. But although many retroviruses went extinct hundreds of thousands or millions of years ...

Phospholipids in the cell membrane help regulate ion channels

Though the cell membrane is a protective barrier, it also plays a role in letting some foreign material in — via ion channels that dot the cell’s surface. Now new research from the Nobel Prize-winning laboratory that first solved the atomic structure of several such channels shows that their fun...

A chemotherapy drug packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors. Radiation therapy and various forms of chemotherapy were all thought to be separate but equal treatments. Now, however, new research is beginning to show that it’s not ...

New Fanconi anemia gene ID'd

An international team of researchers has uncovered the 13th gene to be associated with Fanconi anemia, a rare genetic disease linked to several types of cancer. The identification of the gene helps explain why some young patients develop early and lethal cancer, and also why relatives of these pa...

Chromosome linked to cholesterol absorption

Normal mice don’t have to worry about their cholesterol, but mice from Jan Breslow’s lab at Rockefeller University do. By genetically altering mice to isolate genes that are important for the regulation of cholesterol levels, scientists are helping unravel the genetics of heart disease. His late...