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Ion channels are key to estrogen's effect on neurons

Despite being one of the body's best-studied hormones, there's still a lot we don't know about estrogens. Now, by studying how these sex hormones impact brain cells at the biophysical level, scientists at Rockefeller University say they exert their powerful effects on behavior in part by affectin...
Science News

Measuring awareness is not as simple as a single number

Science fiction describes the crucial difference between a robot and a person as sense of self. But for Rockefeller University’s George Reeke, computers — self or no self — do not yet begin to capture the complexity of the human mind. An article by Reeke and coauthors published recently in Pr...
Science News

HIV-1 kills immune cells in the gut that may never bounce back

People with HIV have been living longer, healthier lives since the development of highly active antiretroviral therapy (or HAART) in 1995. In fact, most patients on the drug regimen do so well that, according to blood tests, their immune cells appear to return to pre-HIV levels. But two new studi...
Science News

Newly discovered class of small RNAs is specifically to reproductive cells

One size does not fit all when it comes to RNA. And now, in addition to long mRNA strands that deliver genetic instructions, and microRNAs (miRNAs) that serve to tweak those instructions and are implicated in everything from insulin production to cancer, scientists have discovered a new player am...
Science News

Structure shows how a key protein in gene activation is controlled

Having good genes is not enough; they each need to be expressed at the right time and place. By solving the structure of a protein called σ, researchers at Rockefeller University reveal a new mechanism by which bacteria prevent premature and precocious activation of their genes. Bacteria use the ...
Science News

Rockefeller lab show that Notch signaling is involved in multiple skin fate decisions

To serve as an effective barrier, skin must form multiple layers that separate internal organs from exposure to the environment. New research from Rockefeller University shows that a well-known signaling pathway, Notch, drives the process by which skin cells form those layers. Starting with the i...
Awards and Honors

Three Rockefeller scientists elected AAAS fellows

Three Rockefeller University scientists have been elected fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society. The election of Arleen Auerbach, Cori Bargmann and Nathaniel Heintz was announced in the AAAS News and Notes section...
Science News

In mice, a new statistical analysis shows a sex hormone influences a drive to explore

Exhaustive searching may not guarantee a compatible mate, but that doesn’t stop most people from trying. Now, new research from Rockefeller University suggests that estrogens may be a driving force. Research in mice, led by George Reeke and Donald Pfaff, has shown that this family of sex hormones...
Science News

Dendritic cells stimulate cancer-cell growth

Since their discovery at Rockefeller University some 30 years ago, dendritic cells have been recognized as key players on the immune-system team, presenting antigens to other immune cells to help them respond to novel insults. Now, Rockefeller scientists have shown that dendritic cells also have ...
Science News

New gene-slicing method targets specific areas of the brain

To understand the role any one gene plays in an organism, scientists rely on knockout mice: They breed a mouse that lacks the gene they are interested in, then observe the effects. It doesn’t always work. Removing a gene from an entire mouse can create many problems, including killing the mouse b...
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