Metabolic Homeostasis in Organelles and Cancer Cells

Event Details

Type

Friday Lecture Series

Speaker(s)

Kivanç Birsoy, Ph.D., Chapman Perelman Associate Professor and head, Laboratory of Metabolic Regulation and Genetics, The Rockefeller University

Speaker bio(s)

Mitochondria are membrane-enclosed organelles with endosymbiotic origins, harboring independent genomes and a unique biochemical reaction network. To perform their critical functions, mitochondria must maintain a distinct biochemical environment and coordinate with the cytosolic metabolic networks of the host cell. This coordination requires them to sense and control metabolites and respond to metabolic stresses. Here, Dr. Birsoy will discuss molecular basis of redox sensing and control in mitochondria and its role in cancer biology.

Kivanç Birsoy received his Ph.D. in molecular genetics in 2009 from Rockefeller, where he was a member of Jeffrey M. Friedman’s lab. He was a postdoc at the Whitehead Institute for Biomedical Research and the Broad Institute of Harvard and MIT, where he was a member of David M. Sabatini’s lab. In 2015 Birsoy returned to Rockefeller as an assistant professor, and he was promoted to associate professor in 2022.

He has received a Vilcek Prize for Creative Promise in Biomedical Science, a Pershing Square Sohn Prize, an AACR NextGen Award for Transformative Cancer Research, an NIH Director’s New Innovator Award, a Sabri Ülker Science Award in Metabolism, and an Irma T. Hirschl/Monique Weill-Caulier Trust Research Award. He has also been named a Blavatnik National Award Finalist in Life Sciences, a Pew-Stewart Scholar for Cancer Research, a March of Dimes Basil O’Connor Scholar, a Searle Scholar, and a Sidney Kimmel Foundation Scholar.

FLS lectures will take place in Caspary Auditorium and virtually via Zoom. We recommend virtual participants log out of VPN prior to logging in to Zoom. Please do not share the link or post on social media. This talk will be recorded for the RU community.

Open to

Tri-Institutional