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Spotlight

Study implicates 60 genes in congenital heart disease, including some that also contribute to related disorders such as autism

A surprising mix of inherited and de novo mutations in 60 genes contribute to 10 percent of CHD cases. Many of these same mutations also contribute to neurodevelopmental disorders including autism. 

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HIV particles emerging from an infected T cell. (Credit: Shutterstock)

Clinical trials show new antibody therapy offers long-lasting HIV control without daily medication

Results presented at Conference on Retroviruses and Opportunistic Infections show that two broadly neutralizing antibodies can keep HIV suppressed for months.

Weill Cancer Hub East launched to unlock immunotherapy's full potential

This bold, multi-institutional collaboration will investigate how metabolism, diet, and gut microbes shape immune responses to cancer.

New mechanism behind adaptive immunity revealed. It could impact how we design vaccines.

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.

New understanding of B cell mutation strategies could have implications for vaccines

New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.

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abstract representation of a circadian clock

Science

It’s not just the winter blues—circadian rhythms have been implicated in diseases from dementia to cancer

Every cell in the body and up to 80 percent of our genes operate under circadian control, significantly influencing our overall health. Here’s some ways to mitigate disruptions to this daily cycle.

Science

A new class of antivirals could help prevent future pandemics

Researchers discovered a vulnerability in viral enzymes that could lead to novel treatments for diseases as diverse as COVID and Ebola, while also minimizing side effects and reducing the odds of d...

Science

Researchers discover a genetic predisposition increasing the risk of breast cancer metastasis

Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.

Science

It’s not just the winter blues—circadian rhythms have been implicated in diseases from dementia to cancer

Every cell in the body and up to 80 percent of our genes operate under circadian control, significantly influencing our overall health. Here’s some ways to mitigate disruptions to this daily cycle.

Science

A new class of antivirals could help prevent future pandemics

Science

Researchers discover a genetic predisposition increasing the risk of breast cancer metastasis

Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.

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Svetlana Mojsov receives Frontiers of Knowledge Award

She shares the award with three other scientists who together laid the groundwork for a new generation of drugs used to treat type 2 diabetes and obesity.

Rockefeller postdocs Paige Arnold and Jim Castellanos are named Hanna Gray Fellows by HHMI

The awards are worth up to $1.5 million each over the course of up to eight years, covering both postdoctoral training and the transition to the start of an independent laboratory as a faculty member.

New center for ambitious neuroscience projects comes to campus

The Miller Brain Observatory, which boasts some of the most advanced imaging technology in the world, is now accepting research proposals.

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