Instruments and Techniques
The DDRC has the capability to support high throughput screening of cellular and biochemical assays using absorbance, fluorescence, fluorescence anisotropy, time-resolved fluorescence, time-gated fluorescence resonance energy transfer, luminescent oxygen channeling and bioluminescence. The bioassay targets can include ion channels, receptors, enzymes, proteins, signaling pathways and cellular processes. Additionally, measurements of drug occupancy are supported with a variety of biophysical techniques.