Event Detail (Archived)
Mathematical Essence of Aging
- This event already took place in January 2024
- A Level Physics Seminar Room, Room A30, Smith Hall Annex (CRC)
Event Details
- Type
- Center for Studies in Physics and Biology Seminars
- Speaker(s)
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Uri Alon, Ph.D., Professor, Weizmann Institute of Science
- Speaker bio(s)
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Aging shows nearly universal quantitative patterns. We explain them using a stochastic ODE for damage production and removal, deduced from experiments on damage dynamics in mice and in individual bacteria, the latter done by us. This simple model explains a wide range of phenomena in human aging and age-related diseases, as well as in model organisms. It pinpoints core molecular and cellular drivers of aging, and suggests interventions that, at least in mice, can compress the relative sick span (fraction of lifespan that an individual is disabled).
- Open to
- Tri-Institutional