Decoding the Cellular Basis of Mammalian Aging at the Whole Organismal Scale
Event Details
- Type
- Monday Lecture Series
- Speaker(s)
-
Junyue Cao, Ph.D., Fisher Center Foundation Assistant Professor and head, Laboratory of Single-Cell Genomics and Population Dynamics, The Rockefeller University
- Speaker bio(s)
-
As we age, certain cell types within the diverse cellular landscape of various organs undergo significant changes. These alterations not only affect the overall function of the organism but also play a critical role in the development of age-related diseases. Mapping these vulnerable cell types is essential for understanding the cellular basis of aging-related pathologies and for identifying potential interventions. Despite recent breakthroughs in high-throughput technologies, accurately quantifying complex biological systems and establishing causal relationships at a cellular level is still a daunting task. In this presentation, Dr. Cao will introduce 1) the development of high-throughput single-cell temporal and spatial genomic approaches to mapping aging-associated vulnerable cell types at the whole organismal scale; 2) the utilization of targeted and systematic perturbation tools to dissect the functional role of the various systems in aging and pinpoint the molecular and cellular drivers regulating the dynamics of aging-associated cell types.
Junyue Cao received his B.S. in biological science from Peking University in 2010. He received his Ph.D. from the University of Washington in 2019, where he also completed a postdoctoral position, both in the lab of Jay Shendure. Cao joined The Rockefeller University as assistant professor in 2020. He has received a William Ackman and Neri Oxman Innovation Fund Award, a Melanoma Research Alliance Young Investigator Award, an NIH Director’s New Innovator Award, a Sagol Network GerOmic Award for Junior Faculty, an Irma T. Hirschl/Monique Weill-Caulier Trust Research Award, a Science & SciLifeLab Prize for Young Scientists, a Western Association of Graduate Schools and University Microfilms International Outstanding Innovation in Technology Award, and a Verna Chapman Young Scientist Award.
MLS lectures are only open to the RU community and will be taking place in Carson Family Auditorium and virtually via Zoom. Virtual participants are required to log in with their RU Zoom account and use their RU email address and password for authentication. We recommend signing out of VPN prior to logging in to the lecture. Please do not share the link or post on social media. - Open to
- Campus Only