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Structural images shed new light on a cancer-linked potassium channel
    Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance. One particular type of potassium channel, called Eag1, has been found...
Postdoc John Maciejowski wins 2016 Regeneron Prize for Creative Innovation
John Maciejowski, a postdoctoral fellow in Titia de Lange’s Laboratory of Cell Biology and Genetics, has received the 2016 Regeneron Prize for Creative Innovation. The award, given by Regeneron Pharmaceuticals, Inc., recognizes innovative young scientists based on proposals they submit that have ...
New faculty member investigates how cells respond to mechanical forces
Whether maneuvering about under their own power, or being pushed and pulled by the surrounding tissue, cells both give and receive mechanical force. The newest addition to Rockefeller University’s faculty, Gregory Alushin, is a biophysicist who investigates how cells use their structural filament...
New faculty member investigates how cells respond to mechanical forces
by Wynne Parry, science writer Whether maneuvering about under their own power, or being pushed and pulled by the surrounding tissue, cells both give and receive mechanical force. The newest addition to Rockefeller University’s faculty, Gregory Alushin, is a biophysicist who investigates ...
Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates
There was a time when Thomas Huber, a molecular biologist at The Rockefeller University, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar’s Laboratory of Chemical Biology and Signal Transduction, became curious about ...
Researchers uncover how “silent” genetic changes drive cancer
At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA. “We’ve long thought of these molecules as little more than middle men participating in the process of translating proteins...
New method gives scientists a better look at how HIV infects and takes over its host cells
Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have long probed this process for insights into biology and disease, but essential details still remain out of reach. A new approach, developed by a team of researchers led by The Rock...
35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller
by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...
Scientists find evidence that cancer can arise from changes in the proteins that package DNA
A mutation that affects the proteins that package DNA—without changing the DNA itself—can cause a rare form of cancer, according to new findings in this week’s Science from researchers at Rockefeller University. The mutation is present in histones, the protein scaffolding around which DNA w...
C. David Allis receives the 2016 Gruber Genetics Prize
C. David Allis, Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics, has won the 2016 Gruber Genetics Prize. He shares the $500,000 award with Michael Grunstein of the University of California, Los Angeles. The award, given by The Gruber Foundation, reco...
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