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Displaying 132 of 2907 articles.

An old antibiotic may combat drug-resistant tuberculosis

Drug-resistant strains of tuberculosis bacteria affect half a million people a year. A compound first discovered in the 1980s may be able to help.

As COVID-19 vaccines emerge, the search for antiviral drugs continues

Scientists are digging through drug libraries of 430,000 compounds, in pursuit of an antiviral drug that can stop the novel coronavirus in its tracks.

How cells use mechanical tension sensors to interact with their environment

In a painstaking experiment, scientists suspended a single protein filament between two microscopic beads. Their results have shed light on an elusive process in which cells receive and respond to mechanical cues.

Rockefeller's Charles M. Rice honored with Nobel Prize for research that contributed to a cure for hepatitis C

Rice will receive the 2020 Nobel Prize in Physiology or Medicine for research that led to a cure for hepatitis C, a viral disease affecting 170 million people worldwide. His lab worked on the virus for three decades and became the first to produce a version of it that could be grown and studied i...

Cancer cells use nerve-cell tricks to spread from one organ to the next

New research suggests that breast and lung tumors metastasize by hijacking a neural signaling pathway, potentially opening the door to better diagnostics and treatments.

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How dividing cells avoid setting off false virus alarms

A new molecular structure explains how cells hold an alarm-triggering protein captive during cell division, preventing cells from targeting their own DNA.

A never-before-seen image of the coronavirus copy machine

The high-resolution 3D image can speed COVID-19 drug discovery.

Amid the rush for COVID-19 drugs, a case for the helicase

The enzyme is essential for the virus to replicate itself inside our cells. Scientists already have ideas for how to block it.

Transparent fish reveal the subtle, cellular dance in which sensory organs take shape

How do primitive cells “know” where to go during development? Scientists studying the fish equivalent of inner-ear hair cells have shown that biochemical and mechanical cues work together to orchestrate a highly complex arrangement.

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Study captures the molecular architect of cells’ infrastructure

Using atomic-resolution technology, scientists have constructed the most detailed view yet of the molecular complex that decides where microtubules form.