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Displaying 183 of 2940 articles.
Early intervention with new treatment provides durable control of HIV-like virus in monkeys
There are more than 25 drugs to control HIV, yet the virus remains one of the world’s biggest health problems. One of the many challenges with existing therapies is that a dormant version of the virus is always lurking in the background, ready to attack the immune system as soon as treatment is i...
A new way to reset gene expression in cancer cells shows promise for leukemia treatment
New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by d...
Scientists discover an unexpected influence on dividing stem cells’ fate
When most cells divide, they simply make more of themselves. But stem cells, which are responsible for repairing or making new tissue, have a choice: They can generate more stem cells or differentiate into skin cells, liver cells, or virtually any of the body’s specialized cell types. As r...
Howard C. Hang receives 2017 Eli Lilly Award in Biological Chemistry
Howard C. Hang, Richard E. Salomon Family Associate Professor and head of the Laboratory of Chemical Biology and Microbial Pathogenesis, has won the 2017 Eli Lilly Award in Biological Chemistry. The prize, given by the American Chemical Society, recognizes outstanding research in biological chemi...
Encouraging clinical results for an antibody drug to prevent or treat HIV
A new biologic agent—the most potent of its kind so far—is showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in people who are at high risk to acquire HIV, the virus that causes AIDS. ...
Study reveals the structure of a protein crucial for DNA replication
Our DNA contains instructions crucial for virtually all forms of life on this planet. But for life to propagate, this blueprint must be copied and passed on to future generations. New findings describing the structure of a key molecule involved in DNA replication place another piece in the puzzle...
Researchers explore how protein production gets distorted in skin cancer
Each cell in the body follows a strict protocol for manufacturing the proteins it needs to function. When a cell turns cancerous, however, its protein production goes off script. A new study led by researchers at the Rockefeller University takes a close look at one way in which this procedure goe...
Antibody combination puts HIV on the ropes
Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body’s ability to control it. But a small group of infected individuals—called elite controllers—possess immune systems capable of defeating the ...
Elaine Fuchs wins 2017 McEwen Award for Innovation
Elaine Fuchs, Rebecca C. Lancefield Professor and head of the Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, has been honored with the 2017 McEwen Award for Innovation. The prize, given by the International Society for Stem Cell Research, recognizes groundbreaking wo...
New research offers clues into how the brain shapes perception to control behavior
What you see is not always what you get. And that, researchers at The Rockefeller University have discovered, is a good thing. “Every time you move your eye, the whole world moves on your retina,” says Gaby Maimon, head of the Laboratory of Integrative Brain Function. “But you don’t perce...
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