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Study explains how an intestinal microbe protects against other, more dangerous bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside. Probiotics consisting of beneficial microorganisms, meanwhile, have the potential to delive...

New research clarifies how cells take in cholesterol and offers insight on Ebola

Cholesterol—that waxy substance incriminated in heart attack and stroke—is a precious commodity for cells. In fact, errors in a cell’s ability to import these rod-like molecules can be fatal. In new work, researchers at The Rockefeller University and their colleagues delved into a pivotal p...

A compound that stops cells from making protein factories could lead to new antifungal drugs

Tiny, abundant biological factories, known as ribosomes, produce the cell’s most fundamental building material: protein. If ribosomes don’t work, cells can’t divide—and this can be an advantage for scientists seeking to develop drugs that target invading organisms, such as pathogenic fungi. ...

Four Rockefeller scientists named 2016 HHMI Faculty Scholars

Four Rockefeller University scientists—Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie—have been named Howard Hughes Medical Institute Faculty Scholars. The Faculty Scholars program, a new collaboration between HHMI, the Simons Foundation, and the Bill & Melinda Gate...

Scientists uncover a clever ranking strategy bacteria use to fight off viruses

Like humans, bacteria come under attack from viruses and rely on an immune system to defend themselves. A bacterial immune system known as CRISPR helps microbes “remember” the viruses they encounter and more easily fend them off in the future. Since researchers first discovered CRISPR in the mid...

Charles M. Rice wins Lasker Award for groundbreaking work on the hepatitis C virus

Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology and head of the Laboratory of Virology and Infectious Disease, has been honored with the 2016 Lasker-DeBakey Clinical Medical Research Award, the country’s most prestigious science prize. Rice shares the award with Ralf F....

Four postdocs honored with 2016 Tri-Institutional Breakout Awards

NEW YORK, NY—Four young life scientists from Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell Medicine are the winners of the 2016 Tri-Institutional Breakout Awards for Junior Investigators. The awards, established last year by three winners of the 2013 Breakt...

New antibody drug continues to show promise for treatment of HIV

Great strides have been made in recent years to develop treatment options for HIV, and the disease can now be controlled with anti-retroviral drugs. But a cure remains elusive and current medications have limitations: they must be taken daily, for life, and can cause long-term complications. Now,...

Postdoc John Maciejowski wins 2016 Regeneron Prize for Creative Innovation

John Maciejowski, a postdoctoral fellow in Titia de Lange’s Laboratory of Cell Biology and Genetics, has received the 2016 Regeneron Prize for Creative Innovation. The award, given by Regeneron Pharmaceuticals, Inc., recognizes innovative young scientists based on proposals they submit that have ...

Michel C. Nussenzweig honored with the 2016 Robert Koch Award

Michel C. Nussenzweig, Zanvil A. Cohn and Ralph M. Steinman Professor and head of the Laboratory of Molecular Immunology, has won the 2016 Robert Koch Award. Nussenzweig will share the €100,000 prize, given by the Robert Koch Foundation of Germany, with Alberto Mantovani from Humanitas University...