Human cells can be coaxed into preventing certain enveloped viruses (including HIV, Ebola, and parainfluenza) from escaping their membranes in the lab, a finding that could lead to novel treatments for many viral diseases.
Studying dozens of naturally occurring and laboratory-selected mutations in SARS-CoV-2, researchers found that the virus will need to pull off a genetic feat to become fully resistant to antibodies.
People who recover from COVID-19 may have better protection than those who received a vaccine, but the benefits of natural immunity do not outweigh the very real risk of disability and death from contracting the disease.
Not every gene that's essential in tuberculosis is also vulnerable to attack. A new study ranks essential genes by vulnerability, allowing researchers to better prioritize future drug targets.
Whenever a cell uses CRISPR to defend itself, there's a chance of mutations creeping into its genetic code. Some of these mutations are harmless; others kill the cell. But fortuitous mutations can occasionally render major human pathogens, such as Staphylococcus aureus, antibiotic resistant.