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Displaying 153 of 2939 articles.
In brief: A close look at how HIV-fighting proteins slow the virus down
A new study sheds light on how the body fights back against HIV by mutating the viral DNA.
New study points the way to therapy for rare cancer that targets the young
Scientists have engineered a mouse model to study a rare and often-fatal form of liver cancer. They’ve used it to clarify what drives these tumors at the molecular level, and discover new drug concepts.
In the fight against viral infection, spelling counts
Scientists have discovered a peculiarity in the genetic code of HIV that might explain how this and other viruses evolved ways to dodge our immune system. The findings could make it possible to develop safer vaccines.
Targeting a single protein might treat a broad range of viruses
Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
Potential new treatment for Fragile X targets one gene to affect many
Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease’s symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
Stress has dramatically different effects on male and female mouse brains
Scientists have found unexpected differences in how male and female mice respond to stress. Their findings are raising big questions about sex discrepancies in the brain and their impact on neuropsychiatric disease.
Titia de Lange to receive 2017 Rosenstiel Award
de Lange is honored for her elucidation of the mechanism of telomere protection and the maintenance of genome stability.
Hunger-controlling brain cells may offer path for new obesity drugs
Within the oldest part of the brain, scientists have found cells in charge of controlling appetite and eating. The discovery could revitalize efforts to develop drugs for obesity that make us less hungry.
Faster-acting antidepressants may finally be within reach
Neuroscientists have taken a major step toward answering longstanding questions about how Prozac and similar drugs act in the brain. Their findings could lead to better antidepressants that don't take weeks to kick in.
In brief: How a microRNA protects against liver cancer
New insights about gene regulation in liver cells could lead to better treatments for a common tumor type.
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