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Science News

Improving the body's "homeland security" against TB

Immune system provides new clue to most life-threatening bacterium The microbe that causes tuberculosis operates the way a human terrorist would. With minimal resources, the TB bacterium skillfully blends in and gains strength before lashing out unexpectedly. This microbe, which claims more human...
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White House Awards National Medal of Science to Rockefeller University's James Darnell

Nation's highest scientific award honors gene regulation pioneer James E. Darnell Jr., M.D., a pioneering researcher in the field of gene regulation, will receive the National Medal of Science, the White House announced today. Darnell is among eight American scientists to receive the award, the n...
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Nobel Prize honors Rockefeller University scientist Roderick MacKinnon for revealing process of electrical signaling in humans and other living organisms

Rockefeller University Professor Roderick MacKinnon, M.D., a biophysicist and X-ray crystallographer whose exquisitely detailed portraits of a class of proteins explain the generation of nerve impulses — the electrical activity that underlies all movement, sensation and thought — is honored this...
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Silence of the genes

New theory explains how gene-silencing "glue" can be removed In addition to nails and screws, a carpenter's bag of tricks includes glue. Nails can be pulled, screws can be removed, but glue is typically permanent. Nature uses its own version of glue to jam a gene's expression when its activity co...
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Leukemia drug Gleevec slows accumulation of major component of senile plaques in cell studies and in guinea pigs

Gleevec, the breakthrough drug for treating chronic myologenous leukemia (CML) and gastrointestinal stromal tumors, slowed the accumulation of the major protein component of senile plaques that characterize Alzheimer's disease, in laboratory cultures of mouse brain cells and guinea pigs. The find...
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Salmonella bacterium uses potent molecular "staples" to change structure of cells it infects

Salmonella, a well-known food-borne bacterium, uses protein "staples" to restructure the shape of the gut cells it invades, forcing these cells to flow around the bacteria and engulf them, researchers at Rockefeller University have discovered. The research, published in the September 26 issue of ...
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Measuring early antibody aptituteds

Rockefeller University study suggests system "checkpoint failure" as one possible cause of autoimmunity Parents and educators pay close attention to preschoolers' aptitudes. Recognition of abilities, or potential difficulties, helps garner proper support for the youngsters as they begin their for...
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Building hair from the ground up

Scientists show how development of hair depends on development of the hair channel There's more to a building than the materials that comprise it; equally important is the foundation that underlies and supports the main structure. Similarly, researchers at The Rockefeller University and the Howar...
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Researchers close in on scientific definition of arousal

For scientists in the field of neurobiology, defining the factors that influence the arousal of brain and behavior is a "Holy Grail." Research published by Rockefeller University scientists in the Aug. 11 issue ofProceedings of the National Academy of Sciences Early Edition is the first to give a...
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Rockefeller University researchers identify protein modules that "read" distinct gene "silencing codes"

Since the time when humans first learned to record their thoughts in written form, codes have kept sensitive information from prying eyes. But conveying information through a code requires someone who can read it as well as write it. The same is true for one of nature's methods for transmitting i...
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