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A genomics study has identified a previously unknown cell type whose blood levels tend to rise and fall in patients with rheumatoid arthritis. The findings could make it easier to manage the disease and help scientists understand its root causes.

Scientists have used advanced technology to “micro-dissect” the first brain cells to perish in Alzheimer’s disease. The result is a short list of genes that could represent new drug targets.

New findings characterize human antibody response to SARS-Cov-2, with implications for convalescent plasma therapy, vaccine design, and antibody-based drugs.


How do primitive cells “know” where to go during development? Scientists studying the fish equivalent of inner-ear hair cells have shown that biochemical and mechanical cues work together to orchestrate a highly complex arrangement.

Llamas make antibodies that are much smaller than their human counterparts, yet still potent. Scientists hope that future drugs based on these molecules could provide new weapons against SARS-CoV-2.

In findings that might lead to better smoking-cessation tools, scientists have shown that manipulating a specific brain receptor can alter a mouse’s nicotine sensitivity.

The discovery of a rare mutation in BRCA2, commonly known as the breast cancer gene, has shed new light on how cells safeguard their genetic material.
 

Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates our own pre-existing genetics.

The condition resembles a rare childhood illness, Kawasaki disease. Researchers are analyzing blood samples to find genetic clues to what might be causing it.

Scientists have discovered how stem cells in the skin maintain their ability to replenish themselves, a process critical for hair growth. The findings suggest that errors in stem cell maintenance might contribute to permanent hair-loss conditions.