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Scientists discover gene mutation that causes children to be born without spleen

The spleen is rarely noticed, until it is missing. In children born without a spleen, that doesn’t happen until they become sick with life-threatening bacterial infections, often within their first year of life. An international team of researchers led by scientists from Rockefeller’s St. Giles ...

Scientists use Nature against Nature to develop an antibiotic with reduced resistance

A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs. The antibiotic, Epimerox, targe...

Mechanism of mutant histone protein in childhood brain cancer revealed

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis’s laboratory at Rockefeller University may bring scientists closer to design...

Researchers create map of “shortcuts” between all human genes

Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the single causative gene. Now, a team of researchers led by Rockefeller Univer...

In sync: stem cells work together to make hair grow, give it color

Your hair may seem unwilling to cooperate some mornings, but at the root of each strand is a tiny partnership of stem cells that work very well together to make hair happen. New research from The Rockefeller University has elucidated how these adult stem cells communicate with each other to make ...

Ant executions serve a higher purpose, research shows

Natural selection can be an agonizingly long process. Some organisms have a way of taking matters into their own hands, or — in the case of the ant species Cerapachys biroi — mandibles. Researchers at The Rockefeller University and University of Paris 13 have found that when a C. biroi ant step...

Changes in population growth, consumption and farming begin to return former farmlands to nature

With the global population racing past seven billion, demographers and world leaders have been concerned with depletion of resources to support everyone. The future, though, may be less bleak than some have feared. Changes in population growth and how farmers use land have brought the world to “p...

Brain displays an intrinsic mechanism for fighting infection

White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. But new research is emerging that individual organs can also play a role in immune system defense, essentially b...

Potent antibodies neutralize HIV and could offer new therapy, study finds

Having HIV/AIDS is no longer a death sentence, but it’s still a lifelong illness that requires an expensive daily cocktail of drugs — and it means tolerating those drugs’ side effects and running the risk of resistance. Researchers at The Rockefeller University may have found something better:...

Neurotransmitters linked to mating behavior are shared by mammals and worms

When it comes to sex, animals of all shapes and sizes tend behave in predictable ways. There may be a chemical reason for that. New research from Rockefeller University has shown that chemicals in the brain — neuropeptides known as vasopressin and oxytocin — play a role in coordinating mating an...