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Displaying 1235 of 2963 articles.
Atomic-level view provides new insight into translation of touch into nerve signals
Whether stubbing a toe or stroking a cat, the sensation of touch starts out as a mechanical force that is then transformed into an electrical signal conveying pain or other sensations. Tiny channels in neurons act as translators by helping to formulate that signal to the brain. However, scientist...
Research suggests how mosquitoes evolved an attraction to human scent
The female mosquitoes that spread dengue and yellow fever didn’t always rely on human blood to nourish their eggs. Their ancestors fed on furrier animals in the forest. But then, thousands of years ago, some of these bloodsuckers made a smart switch: They began biting humans and hitchhiked all ov...
3D deep-imaging advance likely to drive new biological insights
In a significant technical advance, a team of neuroscientists at The Rockefeller University has devised a fast, inexpensive imaging method for probing the molecular intricacies of large biological samples in three dimensions, an achievement that could have far reaching implications in a wide arra...
Research resolves contradiction over protein’s role at telomeres
Mice and humans share a lot more than immediately meets the eye, and their commonalities include their telomeres, protective ends on chromosomes. But in recent years, the role of one particular protein at telomeres has puzzled scientists. New work at Rockefeller University has solved the contradi...
New technique efficiently turns antibodies into highly tuned ‘nanobodies’
Antibodies, in charge of recognizing and homing in on molecular targets, are among the most useful tools in biology and medicine. Nanobodies – antibodies’ tiny cousins – can do the same tasks, for example marking molecules for research or flagging diseased cells for destruction. But, thanks to...
One signal means different things to stem cells versus their progeny
Two listeners might hear the same message, but understand it differently and take different actions in response. Something similar happens within the hair follicle: Stem cells and their progeny react quite differently to an important group of signaling proteins. New experiments at Rockefeller Uni...
Atomic map reveals clues to how cholesterol is made
In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell’s membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production...
Newly discovered brain cells explain a prosocial effect of oxytocin
Oxytocin, the body’s natural love potion, helps couples fall in love, makes mothers bond with their babies, and encourages teams to work together. Now new research at Rockefeller University reveals a mechanism by which this prosocial hormone has its effect on interactions between the sexes, at le...
'Programmable' antibiotic harnesses an enzyme to attack drug-resistant microbes
The multitude of microbes scientists have found populating the human body have good, bad and mostly mysterious implications for our health. But when something goes wrong, we defend ourselves with the undiscriminating brute force of traditional antibiotics, which wipe out everything at once, regar...
New technique reveals a role for histones in cell division
Proteins known as histones give structure to DNA, which coils around them like string on spools. But as is so often the case in biology, it turns out there is more to these structures than meets the eye. Scientists already know histones play a part in controlling the expression of genes, and more...
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