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Being low mouse on the totem pole is tough on murine self-esteem. It turns out it has measurable effects on brain chemistry, too, according to recent experiments at Rockefeller University. Researchers found that mice that were bullied persistently by dominant males grew unusually nervous around n...

The Rockefeller University has received accreditation from The Association for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP), a program that recognizes research organizations’ commitments to providing strong safeguards on behalf of human research participants. Considered ...

Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers. A team of scientists from Paul Greengard’s Rockefeller University laboratory have linked a molecule that stimulates autophagy with the reduction of ...

A tremendous amount of genetics research has been done in flies and tiny worms, in part because scientists have good tools for tweaking these creatures’ DNA. Now, by adapting a powerful method of RNA interference for use in mice, researchers have identified key pathways that cause skin cells to d...

In Civilization and Its Discontents, Sigmund Freud argued that modern society was hard on human psychology, forcing people to get along in unnaturally close quarters. Now newly published research from The Rockefeller University points out a different discontent in the developed world, namely, the...

Some scientists receive prizes for their contributions to science, others find themselves on postage stamps. Rockefeller University’s Jesse Ausubel name is now immortalized in the scientific name of a newly discovered, rare new genus of deep water lobster. Ausubel was given this honor as a tribut...

Despite penicillin and the dozens of antibiotics that followed it, streptococcus bacteria have remained a major threat to health throughout the world. The reason: the superb evolutionary skills of this pathogen to rapidly alter its genetic makeup. In a landmark paper published this week in Scienc...

Stem cells are the incomparably versatile progenitors of every cell in our body. Some maintain this remarkable plasticity throughout the life of an animal, prepared to respond as needed to repair an injury, for instance. Others differentiate into specialized cells, regenerating tissue or facilita...

Scientists identify protein that drives survival of gastrointestinal tumors For patients with gastrointestinal stromal tumors, or GISTs, the blockbuster cancer drug Gleevec has been a reason to hope. Since the drug’s introduction, survival rates have climbed dramatically and recurrence has fal...

Just before a cell divides into two — the basic act of reproducing life — the cellular environment must be exquisitely prepared. The exact timing and localization of the vast array of molecules and processes involved in duplicating chromosomes and separating the offspring from the parent is one ...