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Displaying 1235 of 2962 articles.
A natural approach for HIV vaccine
For 25 years, researchers have tried and failed to develop an HIV vaccine that will generate antibodies to kill the virus before it takes hold. Only four “super antibodies” have been discovered that might do the job, but they have proved impossible to induce in people so far. Now, in research pu...
Scientists discover master regulator of motor neuron firing
When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ideological shift, revealing that one of the most important physiological events in the body — the wiring of ...
Measuring the strength needed to move chromosomes
It’s about as long as the width of a human hair and only half that length across. So it’s tiny — measured in millionths of a meter — and extremely tricky to manipulate. But the meiotic spindle plays so irresistibly important a role in separating our chromosomes during cell division that scie...
Rockefeller University president applauds new U.S. policy on stem cells
Today’s executive order making federal money once again available for research on human embryonic stem cells will accelerate biomedical research and hopefully bring us closer to cures for some of our most devastating diseases, says Rockefeller University president Paul Nurse. “The new policy, w...
Researchers unveil new monkey model for HIV
By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV has already been used to demonstrate one method for preventing infection a...
New protein identified in bacterial arsenal
Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, called virulence factors, play a sophisticated game of mimicry, imitating many of the cells’ normal activiti...
Bacteria-killing enzyme cures mice with fatal pneumonia
Before the advent of antibiotics, pneumonia claimed so many lives — and was so feared — that it was called the “captain of the ship of death.” Now, at a time when the new antibiotics have proved futile against resistant strains of bacteria, researchers at Rockefeller University are using a ...
Brain encodes complex plumes of odors with a simple code
In the real world, odors don’t happen one puff at a time. Animals move through, and subsequently distort, plumes of odor molecules that constantly drift, changing direction as the wind disperses them. Now, by exploring how animals smell odors under naturalistic conditions, Rockefeller University ...
Protein found linking stress and depression
Stress, the ever-present threat to health and happy living, is tough on the brain. If the strain goes on too long, it can lead to debilitating psychological problems. Part of the reason, according to scientists at The Rockefeller University, may have to do with a little-known family of proteins c...
Brain protein may be a target for fast-acting antidepressants
It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11, previously shown to play a role in a person’s susceptibility to depression, activates a seroto...
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