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A DNA-based vaccine shows promise against the avian flu

Though it has fallen from the headlines, a global pandemic caused by bird flu still has the United States’ Centers for Disease Control and Prevention on high alert. Yet, to date, the only vaccines that have proven even semi-effective are produced in chicken eggs, take five to six months to prepar...

New formula predicts how people will migrate in coming decades

Nearly 200 million people now live outside their country of birth. But the patterns of migration that got them there have proven difficult to project. Now scientists at Rockefeller University, with assistance from the United Nations, have developed a predictive model of worldwide population shift...

Neuron in zebrafish may reveal clues to the wiring of the human ear

Developing neurons tend to play the field, making more connections than they will ever need. Then the weakest are cut. But Rockefeller University scientists now show that neurons in young zebrafish — vertebrates, like humans — behave differently: They immediately find a cluster of specialized ce...

Variations in key genes increases Caucasians' risk of heroin addiction

Sometimes, small changes do add up. In the case of addictive diseases, tiny variations in a few genes can increase or decrease the likelihood of some people developing a dependency on heroin. Now, by examining a select group of genetic variants in more than 400 former severe heroin addicts, Rocke...

A blood marker may indicate Alzheimer's risk

A simple blood test capable of predicting if a person might develop Alzheimer’s disease is within sight, and could eventually be used to help scientists reverse onset of the disease in those most at risk. According to new research by Rockefeller University scientists and their colleagues at Colum...

Abuse of painkillers can predispose adolescents to lifelong addiction

No child aspires to a lifetime of addiction. But their brains might. In new research to appear online in the journal Neuropsychopharmacology today, Rockefeller University researchers reveal that adolescent brains exposed to the painkiller OxyContin can sustain lifelong and permanent changes in th...

C. Erec Stebbins awarded prestigious EUREKA grant

C. Erec Stebbins, associate professor at The Rockefeller University, has been awarded an inaugural EUREKA grant from the National Institutes of Health for a project aimed at exploiting a bacteria-based “nanosyringe” as a means of delivering proteins into specific cells for therapeutic purposes. ...

Clinical study to examine role of vitamin D in kidney disease

Vitamin D is the key to preventing rickets and osteoporosis, but Rockefeller University scientists suspect it may also play a role in heading off atherosclerosis in people with chronic kidney disease. In a new clinical study, investigators at The Rockefeller University Hospital are examining pati...

Newly uncovered cells may be critical in psoriasis

Psoriasis, one of humanity’s oldest known diseases, has also been one of its most misunderstood. But in a new study that could change researchers’ perspective of the skin disorder and potentially lead to powerful new drug targets, Rockefeller University scientists have found that the source of p...

Rifamycin antibiotics attack tuberculosis bacteria with walls, not signals

Amid concerns about the rising number of new tuberculosis cases worldwide, researchers at Rockefeller University and their collaborators have reexamined and disproved a theory that describes how a potent class of antibiotics kills a deadly form of bacteria. The findings, which will appear in this...