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Displaying 1235 of 2962 articles.
Newly solved structure reveal how cells resist oxygen damage
The sun’s rays give life, but also take it away. Singlet oxygen, a byproduct of the photosynthetic process by which certain cells convert sunlight into energy, is a highly toxic and reactive substance that tears cells apart. Now, in a study that took more than five years to complete, Rockefeller ...
Viewing dye-packed vesicles causes them to explode
It’s a long-standing question: Can just the act of observing an experiment affect the results? According to a new study by Rockefeller University scientists, if the experiment uses a fluorescent dye called acridine orange, the answer is a resounding “yes.” Cells use a process called exocyto...
Sizing cells up: Researchers pinpoint when a cell is ready to reproduce
For more than 100 years, scientists have tried to figure out the cell size problem: How does a cell know when it is big enough to divide? In research conducted in budding yeast (Saccharomyces cerevisiae), scientists at Rockefeller University have now identified the cellular event that marks the m...
New cell death pathway involved in sperm development
Heavy and bulky sperm would not be good swimmers. To trim down, sperm rely on cell death proteins called caspases, which facilitate the removal of unwanted cellular material and radically remodel these cells into their sleek, light shape. New research from scientists at the Howard Hughes Medical ...
Gene determines whether male body odor smells pleasant
To many, urine smells like urine and vanilla smells like vanilla. But androstenone, a derivative of testosterone that is a potent ingredient in male body odor, can smell like either — depending on your genes. While many people ascribe a foul odor to androstenone, usually that of stale urine or st...
Dendritic cells stimulate production of immune-repressing T cells
Regulatory T cells (also known as T regs) suppress some of the immune system’s more inappropriate responses, preventing it from attacking the body’s own tissues and stifling its activity once invading microbes have been fought off. But while researchers knew that these cells could be exploited f...
A global view: Researchers build microRNA atlas
Building a comprehensive microRNA expression atlas is not easy. Just ask the Rockefeller University scientists who, in a massive collaborative effort involving 50 investigators from six countries, led the project. In three years, they catalogued microRNA expression patterns in more than 250 healt...
Core tenets of the "histone code" are universal
In one of biology’s most impressive engineering feats, specialized proteins called histones package some six-and-a-half feet of human DNA into a nucleus that averages just five microns in diameter. That’s only 0.0001969 inches. DNA wraps around histone proteins, which are then chemically modifie...
Common immune cell marker shown to be off target
A marker that scientists have depended on for over 15 years to pick out a group of immune cells in the skin has been misidentifying them, Rockefeller University scientists report. In order for scientists who study psoriasis and other skin disorders to understand the inner workings of disease, the...
From frogs to humans, brains form the same way
It’s a critical juncture in an embryo’s development: the moment that a brain and nervous system begin to form from a mass of unspecialized cells. Scientists had believed that mammals and amphibians, distinctly different animals, have distinctly different developmental patterns when it comes to t...
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