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Displaying 1234 of 2961 articles.
Although few people in the United States have reason to have heard of it, leishmaniasis is a parasitic disease that occurs in 88 different tropical and subtropical countries. Yet despite its prevalence, there is currently no vaccine to prevent transmission. Now, research by Rockefeller University...

A protein long known to be involved in protecting a cell from genetic damage has been found to play an even more important role in protecting the cell’s offspring. New research shows that the protein, known as ATM, is not only vital for helping repair double-stranded breaks in the DNA of immune c...

Ion channels are small passageways that control the movement of electrically charged particles across a cell’s membrane. But they’re persnickety gatekeepers: Each channel allows only one kind of ion to flow through. Now, new research from Rockefeller University reveals the thermodynamics behind ...

Rockefeller University investigators say that a molecule that helps transport cargo inside nerve cells may have another, critically important, role related to how developing neurons sprout the projections that relay electrical signals within the brain. In the June 6 issue of The EMBO Journal, re...

Dendritic cells help direct the body’s immune response by presenting invading antigens to T cells so they know what to attack. But an ongoing debate exists about where dendritic cells originate and how they multiply, especially in the spleen and lymph system. Now, in a paper published in this mon...

Antibacterial resistance doesn’t happen overnight. But until recently nobody knew exactly how long it took — or how it happened at all. Now, by studying blood taken from a single patient over a period of months, Rockefeller University researchers have been able to trace how a common strain of ba...

Most animals appear symmetrical at first glance, but we’re full of internal lopsidedness. From the hand used to pick up a pencil or throw a baseball, to where language is generated in the brain, to the orientation of our internal organs, humans are a glut of asymmetries. Worms aren’t so differen...

Animals have biological clocks with a cycle of about 24 hours — these circadian rhythms allow them to align their physiology and behavior to the earth’s rotation. Now new research from Rockefeller University shows that the same molecular clock responsible for helping flies sync themselves with p...

Depressed mice, like depressed humans, often appear listless and antisocial — the result of aberrant levels of brain chemicals such as serotonin. The most commonly prescribed antidepressant drugs, Prozac and other drugs of its class, act to normalize levels of serotonin. But by comparing mice tha...

From bacteria to humans, every organism must replicate its DNA. This basic process, which occurs millions of times a day in an average mammal, is driven by three core protein complexes that act as tiny machines, zipping along an unwound strand of DNA to assemble a duplicate copy. New research fro...