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An embryonic cell’s fate is sealed by the speed of a signal
When embryonic cells get the signal to specialize the call can come quickly. Or it can arrive slowly. Now, new research from Rockefeller University suggests the speed at which a cell in an embryo receives that signal has an unexpected influence on that cell’s fate. Until now, only concentration o...
Jean-Laurent Casanova honored with 2014 Sanofi-Institut Pasteur Award
Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University, has been named a 2014 Sanofi-Institut Pasteur Award winner for his paradigm-shifting discovery of the role of single-gene mutations in infectious diseases,...
Small RNAs in blood may reveal heart injury
Like clues to a crime, specific molecules in the body can hint at exposure to toxins, infectious agents or even trauma, and so help doctors determine whether and how to treat a patient. In recent years, tiny pieces of RNA called microRNAs have captured scientific attention for their potential as ...
Medical innovation requires federal support and structural improvements, Marc Tessier-Lavigne tells members of Congress
Two distinct but complementary types of research produce medical innovation: basic science in academic labs and applied work by private sector companies, Rockefeller President Marc Tessier-Lavigne told members of a U.S. House of Representatives subcommittee on July 17. Increased federal funding f...
Discovery of pro-metastasis protein reveals mysterious link to neurodegeneration
Researchers have identified a protein that makes breast cancer cells more likely to metastasize. What's more, the protein appears to trigger cancer's spread in part by blocking two other proteins normally linked to neurodegeneration, a finding that suggests a tie between two of the most common di...
In the News - WSJ - 7/28/14
Wanted: Biotech Startups in New York City   "A lot of the legal and commercial groundwork has been established between Accelerator and its partner institutions, which should help speed the business-development process, said Marc Tessier-Lavigne, president of Rockefeller University."
In the News
Peter Marler, Graphic Decoder of Birdsong, Dies at 86   “Dr. Marler was one of the first ethologists to produce graphic snapshots of birdsong — streaks of ink on paper, like an electrocardiogram, showing the wave-frequency, modulation and pitch of various calls and songs. From that data, Dr. ...
Researchers create the first model of the DNA ‘replication fork’
Human cells make new copies of their DNA billions of times each day, a crucial process upon which life itself depends. However, scientists do not fully understand how cells unzip the double-stranded DNA molecule before replicating both halves of it. New work at Rockefeller may help change that. F...
Nat Immunol 2014 Jul 21
Nature Immunology online: July 21, 2014 Type I and type II Fc receptors regulate innate and adaptive immunity Andrew Pincetic, Stylianos Bournazos, David J DiLillo, Jad Maamary, Taia T. Wang, Rony Dahan, Benjamin-Maximillian Fiebiger and Jeffrey V. Ravetch
Cell 158, 300–313
Cell 158, 300–313 Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility Paul Andrew Muller, Balázs Koscsó, Gaurav Manohar Rajani, Korey Stevanovic, Marie-Luise Berres, Daigo Hashimoto, Arthur Mortha, Marylene Leboeuf, Xiu-Min Li, Daniel Mucida, E. Richa...
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