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New technique in RNA interference cuts time and cost in genetic screens
There is a new contender in the field of gene discovery, and it’s giving knockout mice a run for their money. Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades ...
Structural biologist, interested in ribosome assembly, to join Rockefeller faculty
At the heart of the central dogma of biology — that DNA makes RNA and RNA makes proteins — is the ribosome. Ribosomes serve as a cell’s protein factories, linking amino acids together into complex proteins according to instructions encoded in the cell’s messenger RNAs. It’s a process that ...
Nature online: August 14, 2013
Nature online: August 14, 2013 RNAi screens in mice identify physiological regulators of oncogenic growth Slobodan Beronja, Peter Janki, Evan Heller, Wen-Hui Lien, Brice E. Keyes, Naoki Oshimori and Elaine Fuchs
Proceedings of the National Academy of Sciences USA online: August 8, 2013
Proceedings of the National Academy of Sciences USA online: August 8, 2013 UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling Carlene Moore, Ferda Cevikbas, H. Amalia Pasolli, Yong Chen, Wei Kong, Cordula Kempkes,...
Researchers find molecule that causes sunburn pain
The painful, red skin that comes from too much time in the sun is caused by a molecule abundant in the skin’s epidermis, a new study published in the Proceedings of the National Academy of Sciences shows. Blocking the molecule, called TRPV4, greatly protects against the painful effects of sunburn...
Nature Immunology online: August 4, 2013
Nature Immunology online: August 4, 2013 Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens Ansuman T. Satpathy, Carlos G. Briseño, Jacob S. Lee, Dennis Ng, Nicholas A. Manieri, Wumesh K.C., Xiaodi Wu, Stephanie R. Thomas, Wan-...
In the News
Engineering in Service of a Dark Art   "Biology graduate student Tom McDonagh, of Rockefeller University, likes working with light. For his Ph.D. he built a spinning microscope that uses centrifugal force to test the gripping power of different molecules. McDonagh also innovates with light outsid...
Nature online: July 31, 2013
Nature online: July 31, 2013 Completion of the entire hepatitis C virus life cycle in genetically humanized mice Marcus Dorner, Joshua A. Horwitz, Bridget M. Donovan, Rachael N. Labitt, William C. Budell, Tamar Friling, Alexander Vogt, Maria Teresa Catanese, Takashi Satoh, Taro Kawai, Shizuo Akir...
Proceedings of the National Academy of Sciences USA online: July 29, 2013
Proceedings of the National Academy of Sciences USA online: July 29, 2013 Behavioral diversity in microbes and low-dimensional phenotypic spaces David Jordan, Seppe Kuehn, Eleni Katifori and Stanislas Leibler  
Proceedings of the National Academy of Sciences USA online: July 29, 2013
Proceedings of the National Academy of Sciences USA online: July 29, 2013 Behavioral diversity in microbes and low-dimensional phenotypic spaces David Jordan, Seppe Kuehn, Eleni Katifori and Stanislas Leibler  
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