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Science News

PLD1 protein is implicated in Alzheimer's brain damage

Most current Alzheimer’s drugs target molecules responsible for memory formation. But while helpful at slowing and even reversing memory loss, this approach doesn’t address the root of the problem: plaques that build amid brain cells, causing them to weaken and die. In back-to-back papers pub...
Science News

Genetic studies in mice yield clues to how heart disease is inherited

Heart disease tends to run in families, and scientists have long known that genetics play an important role. Now, new research in mice, from the laboratory of Rockefeller’s Jan L. Breslow, shows that the genetics of heart disease are more complicated than previously thought. In a study led by Dan...
Science News

Newly discovered immune cell partially responsible for psoriasis

In a discovery that may help shape new treatments for psoriasis, scientists at Rockefeller University have found a new type of immune cell that may be critical in producing inflammation and tissue damage in the skin. Psoriasis occurs when white blood cells react to an unknown trigger and inappro...
Science News

'Geneless' enzyme is key to how bacteria intack

To infect, bacteria must first stick. Several proteins on their cell wall surface are there simply to attach themselves to the surrounding tissues of their hosts, such as the warm, moist, inviting ones at the back of your throat. Now new research from Sung Lee and Vincent Fischetti in Rockefeller...
Science News

For insect cells, like mouse cells, one protein decides between life and death

Cells are given life by mitochondria, an organelle that provides them with all the energy they need. But while mitochondria giveth, they also taketh away — when a cell’s time is up, they release molecules that start a cascade ending in death. At least that’s how it works in humans, mice and ot...
Science News

'Hitchhiking' chromosomes yield new theory of cell division

From the moment the cell was discovered, scientists have been dissecting the methodical, multi-step process by which they duplicate themselves. This week, Rockefeller researchers studying one component of this process — how a cell’s chromosomes move in preparation for division — announce a dis...
Science News

Study shows a fundamental difference between how insects, mammals detect odors

When smelling their favorite foods, both humans and insects usually go with their instinct and try to find the source. However, according to new research by Leslie Vosshall and colleagues at Rockefeller University, when it comes to smell, that’s about the only thing that they have in common. Voss...
Campus News

'U.S. biomedical research under seige,' says Rockefeller University president Paul Nurse

In an editorial published this week in one of the nation’s leading biomedical journals, Cell, Rockefeller University President Paul Nurse suggests that the scientific research enterprise in the United States is in danger of suffering major damage as a result of stagnated funding and the failure o...
Science News

New research shows how proteins make biological clock tick

Just as a pocket watch requires a complex system of gears and springs to keep it ticking precisely, individual cells have a network of proteins and genes that maintain their own internal clock—a daily rhythm that, in humans, regulates metabolism, cell division and hormone production, as well as t...
Awards and Honors

Three Rockefeller scientists receive 2005 Mayor's awards

Three of Rockefeller’s scientists were honored today with 2005 New York City’s Mayor’s Awards for Excellence in Science and Technology: Jan Breslow, Mitchell Feigenbaum and Leslie Vosshall. Jan Breslow is recognized with the Award in Biological and Medical Sciences for his pioneering work on ...
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