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Immunity runs amok without Csk

Deconstructing inflammation at the molecular level Inflammation is emerging as a new window on chronic diseases such as cancer, heart ailments and autoimmunity. Two Rockefeller University scientists have recently revealed one of the molecular keys to inflammation. Their discovery may help clinici...

Rockefeller researchers identify how protein linked to cancer correct cells when they divide

A protein, which has been linked to tumor formation when it is overproduced, in normal amounts actually helps correct errors during cell division that can lead to cancer and other diseases, according to new research by scientists at Rockefeller University in the March issue of Nature Cell Biology...

Biological clock scientist takes on VP for Academic Affairs position at Rockefeller University on March 1

Rockefeller University scientist Michael W. Young, who investigates the genetic pathways that enable the body's biological clock to tick, will become Rockefeller University's Vice President for Academic Affairs on March 1. "Mike Young has the respect of everyone at Rockefeller as a scientist, lea...

Natural killer cells are made, not born

First evidence of immune cell's activation potential in infection, tumor control Call it the immune system's version of nature versus nurture. For years, scientists regarded natural killer cells as a blunt instrument of the body's immune defense system. Born to kill, these cells were thought to ...

Feeder-free system for maintaining embryonic stem cells pioneered at Rockefeller University

Molecule developed from marine mollusk overcomes risks of current methods Human embryonic stem cell (HESC) lines, or cultures, in the U.S. are not suitable for use in the budding field of regenerative medicine. Their creation using mouse feeder cells, a specialized growth medium, allows scientist...

Internationally renowned neurobiologist to join Rockefeller University; Cori Bargmann discovered "matchmaker" molecule

Cornelia I. Bargmann, Ph.D., universally recognized as a scientific leader in research on how the circuitry of the brain is organized and influences behavior, will join The Rockefeller University, its President Paul Nurse, Ph.D., announced today. Currently an investigator at the Howard Hughes Med...

Scientists finally pry stubborn cellular door ajar

Details of cystic fibrosis chloride channel exposed for first time Imagine a door with key and combination locks on both sides, back and front. Now imagine trying to unlock that door blind-folded. This is the challenge faced by David Gadsby, Ph.D., and his Rockefeller University colleagues, who f...

New science of "epigenetics" advanced by findings reported in Molecular Cell

New science of "epigenetics" — which explores how physical characteristics of cells and their chromosomes can be inherited separate from the DNA sequence — is advanced by recent findings reported in Molecular Cell Since Gregor Mendel first crossed strains of peas in his garden over 100 years ag...

New method identifying and isolating stem cells developed

Cells may help researchers in skin and hair therapies; tool can be used to find other body stem cells, including cancer stem cells Researchers at the Howard Hughes Medical Institute at The Rockefeller University have discovered a new method to track and isolate elusive stem cells. The new animal ...

Trial of new investigational AIDS vaccine begins in New York and Rochester

Healthy Volunteers Sought for New AIDS Vaccine Research Effort The Aaron Diamond AIDS Research Center (ADARC), an affiliate of The Rockefeller University, and the International AIDS Vaccine Initiative (IAVI) announced today that they have begun a human trial of a new investigational vaccine to pr...