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Natural killer cells are made, not born
First evidence of immune cell's activation potential in infection, tumor control Call it the immune system's version of nature versus nurture. For years, scientists regarded natural killer cells as a blunt instrument of the body's immune defense system. Born to kill, these cells were thought to ...
Feeder-free system for maintaining embryonic stem cells pioneered at Rockefeller University
Molecule developed from marine mollusk overcomes risks of current methods Human embryonic stem cell (HESC) lines, or cultures, in the U.S. are not suitable for use in the budding field of regenerative medicine. Their creation using mouse feeder cells, a specialized growth medium, allows scientist...
Internationally renowned neurobiologist to join Rockefeller University; Cori Bargmann discovered "matchmaker" molecule
Cornelia I. Bargmann, Ph.D., universally recognized as a scientific leader in research on how the circuitry of the brain is organized and influences behavior, will join The Rockefeller University, its President Paul Nurse, Ph.D., announced today. Currently an investigator at the Howard Hughes Med...
Scientists finally pry stubborn cellular door ajar
Details of cystic fibrosis chloride channel exposed for first time Imagine a door with key and combination locks on both sides, back and front. Now imagine trying to unlock that door blind-folded. This is the challenge faced by David Gadsby, Ph.D., and his Rockefeller University colleagues, who f...
New science of "epigenetics" advanced by findings reported in Molecular Cell
New science of "epigenetics" — which explores how physical characteristics of cells and their chromosomes can be inherited separate from the DNA sequence — is advanced by recent findings reported in Molecular Cell Since Gregor Mendel first crossed strains of peas in his garden over 100 years ag...
New method identifying and isolating stem cells developed
Cells may help researchers in skin and hair therapies; tool can be used to find other body stem cells, including cancer stem cells Researchers at the Howard Hughes Medical Institute at The Rockefeller University have discovered a new method to track and isolate elusive stem cells. The new animal ...
Trial of new investigational AIDS vaccine begins in New York and Rochester
Healthy Volunteers Sought for New AIDS Vaccine Research Effort The Aaron Diamond AIDS Research Center (ADARC), an affiliate of The Rockefeller University, and the International AIDS Vaccine Initiative (IAVI) announced today that they have begun a human trial of a new investigational vaccine to pr...
Genes may protect against heart disease rather than be harmful as previously thought
A genetic pathway whose activity was suspected to advance heart disease by increasing inflammation in the blood vessels and arteries feeding the heart may actually protect against it at least in laboratory mice, reports a team of Rockefeller University scientists led by Jan Breslow, M.D., in the ...
Mouse studies show brain's "master molecule" produces same behavior from three different psychostimulant drugs
Findings may lead to new drug targets for treating schizophrenia A mouse study reported in this week's Science magazine shows that three drugs, each acting on a different chemical transmitter in the brain, all produce the same schizophrenia-like symptoms by acting on a single "master molecule" in...
By the year 2050, human population could add 2.6 billion people, reports Rockefeller scientist Joel E. Cohen
It took from the beginning of time until 1950 to put the first 2.5 billion people on the planet. Yet in the next half-century, an increase that exceeds the total population of the world in 1950 will occur. So writes Joel E. Cohen, Ph.D., Dr.P.H., professor and head of the Laboratory of Population...
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