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The rockefeller university

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By amplifying cell death signals, scientists make precancerous cells self-destruct
When a cell begins to multiply in a dangerously abnormal way, a series of death signals triggers it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the...
A snooze button for the circadian clock
We may use the snooze button to fine-tune our sleep cycles, but our cells have a far more meticulous and refined system. Humans, and most other organisms, have 24-hour rhythms that are regulated by a precise molecular clock that ticks inside every cell. After decades of study, researchers are sti...
Researchers solve structure of an enzyme vital for DNA repair
When dividing cells copy their DNA, mistakes can — and do — occur. To compensate, cells have a built-in system to correct these errors. That correction process isn’t thoroughly understood, but researchers are piecing it together bit by bit. Now, in the latest step toward solving this puzzle, R...
Molecular bridge serves as a tether for cell's nucleus
A cell’s nucleus — home of it its most precious contents — is a delicate envelope that, without support, is barely able to withstand the forces that keep it in place. Now, researchers have discovered a network of molecules in the nuclear membrane that provide the nucleus with rigidity and also...
A positive-feedback system ensures that cells divide
In the life of every cell, there’s a point of no return. Once it enters the cell cycle and passes a checkpoint known as “Start,” a cell will follow the steps it needs to divide — no matter what changes might occur in its environment. Now, in research appearing in the July 17 issue of Nature...
In lean times, flies can't survive without their sense of smell
It’s not just bomb-sniffing dogs; animals everywhere rely on their sense of smell. Now, Rockefeller University researchers show just how important olfaction is, proving that fruit flies with a normal sense of smell have a survival advantage over those that don’t. The findings, to appear in the J...
Eroded telomeres are behind a rare premature aging syndrome
Each time a cell divides, the protective caps at the ends of chromosomes shorten — and when these caps are gone, so are we. Now, by using an unconventional strategy to shorten telomeres in mice, researchers at Rockefeller University have not only created the first faithful mouse model for studyin...
Rockefeller Archive center becomes an independent organization
After 34 years as part of the university, The Rockefeller Archive Center, which catalogs and stores the university’s administrative and scientific records and also handles archival material from several other organizations and from the Rockefeller family, has become an independent organization. E...
New fundraising goal set at $750 million
by ZACH VEILLEUX With $490 million raised toward its original $500 million campaign goal, the university’s Board of Trustees has decided to be 50 percent more ambitious. On June 4, they voted to add $250 million and two years to the Campaign for Collaborative Science, the fundraising initiative t...
Archive center goes its own way
by ZACH VEILLEUX After 34 years as part of the university, The Rockefeller Archive Center, which catalogs and stores the university’s administrative and scientific records and also handles archival material from several other organizations and from the Rockefeller family, has become an independen...
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