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A class of ineffective immune cells may be driving Alzheimer’s disease, a finding that could both explain why APOE4 gene increases the risk of the disease and why a new drug can impact it.

LINE-1 is associated with disease and aging. The Rout lab has uncloaked the core of its key protein, pointing the way towards therapeutic targets.

She was known by her colleagues for both her committed professionalism and her generous spirit.

Luciano Marraffini’s research helped lay the groundwork for the newly FDA-approved CRISPR-based therapy for sickle cell anemia. He reflects on how we got here—and where the science is going next.

It also reduces the cost of a million single-cell transcriptomes from $10,000 to $700—and the time necessary down to about a day.

By focusing on the emergent features of cell collectives, instead of individual cells, scientists forge a new path for understanding how organs develop their architecture.   

From plumbing the depths of wound repair to tackling how songbirds solve problems, here are some fascinating discoveries that came out of Rockefeller in 2023.

Carlo Yuvienco, the inaugural director of the university’s new Ford Center Incubator, on how the new space will help translate research breakthroughs into market-ready biomedical innovations.

Mojsov’s research directly led to blockbuster drugs like Ozempic and Wegovy. She talks about the long quest for proper credit and lessons that can be learned from her experience.

Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.