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Using geometry, researchers coax human embryonic stem cells to organize themselves

About seven days after conception, something remarkable occurs in the clump of cells that will eventually become a new human being. They start to specialize. They take on characteristics that begin to hint at their ultimate fate as part of the skin, brain, muscle or any of the roughly 200 cell ty...
Science News

Potential Alzheimer’s drug prevents abnormal blood clots in the brain

Without a steady supply of blood, neurons can’t work. That’s why one of the culprits behind Alzheimer’s disease is believed to be the persistent blood clots that often form in the brains of Alzheimer’s patients, contributing to the condition’s hallmark memory loss, confusion and cognitive ...
Science News

Sequencing efforts miss DNA crucial to bacteria’s disease causing power

Genomic sequencing is supposed to reveal the entire genetic makeup of an organism. For infectious disease specialists, the technology can be used to analyze a disease-causing bacterium to determine how much harm it is capable of causing and whether or not it will be resistant to antibiotics. But ...
Awards and Honors

Jean-Laurent Casanova to receive 2014 Robert Koch Award

Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has been awarded the 2014 Robert Koch Award from the Berlin, Germany based Robert Koch Foundation. Casanova shares the prize with Alain Fischer from the Collège de France and Imagine Institute and th...

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment (June 22, 2014)

Nature Cell Biology online: June 22, 2014 The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment Mu He, Radhika Subramanian, Fiona Bangs, Tatiana Omelchenko, Karel F. Liem Jr, Tarun M. Kapoor & Kathryn V. Anderson

Science 344, 1401-1405

Science 344, 1401-1405 | Newswire HIV-1–induced AIDS in monkeys Theodora Hatziioannou,Gregory Q. Del Prete, Brandon F. Keele, Jacob D. Estes, Matthew W. McNatt, Julia Bitzegeio, Alice Raymond, Anthony Rodriguez, Fabian Schmidt, C. Mac Trubey, Jeremy Smedley, Michael Piatak Jr., Vineet N. KewalRam...
Science News

New monkey model for AIDS offers promise for medical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees. While this would qualify as good news for most mammals, for humans this fact has made the search for effective treatments and vac...
Campus News

Structural biologist, focused on cell transport machinery, to join faculty

Jue Chen, a structural biologist whose research focuses on transporter proteins that act as the cell’s pumping machinery, will join The Rockefeller University as professor and head of laboratory in July. Chen, currently a tenured professor of biology at Purdue University in Indiana and a Howard H...

Netrin-1 controls sympathetic arterial innervation

Journal of Clinical Investigation online: June 15, 2014 Netrin-1 controls sympathetic arterial innervation Isabelle Brunet, Emma Gordon, Jinah Han, Brunella Cristofaro, Dong Broqueres-You, Chun Liu, Karine Bouvrée, Jiasheng Zhang, Raquel del Toro, Thomas Mathivet, Bruno Larrivée, Julia Jagu, Laur...

DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets

Nature Chemical Biology online: June 15, 2014 DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets Corynn Kasap, Olivier Elemento and Tarun M. Kapoor
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