Skip to main content

The rockefeller university

News & HighlightsNews
Dendritic cells stimulate production of immune-repressing T cells
Regulatory T cells (also known as T regs) suppress some of the immune system’s more inappropriate responses, preventing it from attacking the body’s own tissues and stifling its activity once invading microbes have been fought off. But while researchers knew that these cells could be exploited f...
Construction begins on new Collaborative Research Center
After nearly two years of planning, construction is under way on The Rockefeller University’s new Collaborative Research Center, a building and renovation project that will transform two historic limestone and masonry buildings into modern open-plan laboratories connected by a dramatic six-story ...
A global view: Researchers build microRNA atlas
Building a comprehensive microRNA expression atlas is not easy. Just ask the Rockefeller University scientists who, in a massive collaborative effort involving 50 investigators from six countries, led the project. In three years, they catalogued microRNA expression patterns in more than 250 healt...
Core tenets of the "histone code" are universal
In one of biology’s most impressive engineering feats, specialized proteins called histones package some six-and-a-half feet of human DNA into a nucleus that averages just five microns in diameter. That’s only 0.0001969 inches. DNA wraps around histone proteins, which are then chemically modifie...
Common immune cell marker shown to be off target
A marker that scientists have depended on for over 15 years to pick out a group of immune cells in the skin has been misidentifying them, Rockefeller University scientists report. In order for scientists who study psoriasis and other skin disorders to understand the inner workings of disease, the...
From frogs to humans, brains form the same way
It’s a critical juncture in an embryo’s development: the moment that a brain and nervous system begin to form from a mass of unspecialized cells. Scientists had believed that mammals and amphibians, distinctly different animals, have distinctly different developmental patterns when it comes to t...
Food supply affects bacteria's response to temperature
As a population of bacteria grows, it can become desperate. When their food supply dwindles, bacteria must either forage for new sources of nutrients or slow their metabolism. That’s why, at a critical bacterial concentration,Escherichia coli use a chemical signal to collectively swim from warm a...
Mice use specialized neurons to detect carbon dioxide in the air
For mice, carbon dioxide often means danger — too many animals breathing in too small a space or a hungry predator exhaling nearby. Mice have a way of detecting carbon dioxide, and new research from Rockefeller University shows that a special set of olfactory neurons is involved, a finding that m...
Blood-clotting protein may be new target for Alzheimer's drugs
Despite the rapid rise of Alzheimer’s disease — the Alzheimer’s Association predicts as many as 7.7 million cases by 2030 — there are no preventative treatments available, few in the pharmaceutical pipeline, and those drugs being developed all share the same two molecular targets. Now Rockef...
Two proteins found on telomeres control DNA damage response pathways
No sooner had cells evolved linear chromosomes than they had a life-threatening problem to solve. To the machinery that repairs broken DNA, chromosome ends look a lot like breaks in need of mending, so they could elicit a DNA damage response that would ultimately be lethal to cells. Telomeres, se...
View
View