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Rockefeller University researchers decipher the shape of a sodium/potassium ion pump
Proteins studding the surface of cell membranes are vital to the cell, transmitting signals and maintaining equilibrium by moving charged molecules — ions — from one side to the other. Some of these proteins even use energy by acting as pumps, specialized channels with gates that strictly open o...
Study of birds suggests method of learning affects how the brain adds neurons
Teaching may be the world’s most noble profession. But new research from Fernando Nottebohm’s Rockefeller University laboratory shows that, in birds, the presence of a teacher may actually limit mental flexibility. Thirty days after they are born, male zebra finches start to imitate and learn t...
Study of hair follicles leads researchers to a key stem cell protein
With all the excitement over what stem cells can become, a few basic questions tend to be overlooked: Where do they come from? And how do they survive? They are important questions, and the answer has relevance to potential stem cell therapies and to cancer. In a recent paper in Science, Rockefel...
HIV gets a makeover: A few adjustments to the AIDS virus could alter the course of research
The slow pace of AIDS research can be pinned, in no small part, on something akin to the square-peg-round-hole conundrum. The HIV-1 virus won’t replicate in monkey cells, so researchers use a monkey virus — known as SIVmac, or the macaque version of simian immunodeficiency virus — to test pote...
New function for protein links plant's circadian rhythm to its light-detection mechanism
They may not sleep — or dream — but plants do have day-night cycles just like animals. Their internal timekeepers tell them how long the days are, helping the plants control photosynthesis and flowering. Now, new research from Nam-Hai Chua’s laboratory at Rockefeller University has identified ...
Rockefeller University receives $45 million NIH grant for clinical, translational science
The National Center for Research Resources at the National Institutes of Health announced today that Rockefeller University has been awarded one of the first Clinical and Translational Science Awards (CTSA), a component of the NIH Roadmap designed to transform clinical and translational research ...
Animal study suggests two amino acids may modulate addictive behavior
For some, living without alcohol, cigarettes or even coffee is a daily struggle. Others can give up their vices without ever looking back. From a biological standpoint, the difference may be as slight as a single amino acid, suggests new research from the Rockefeller University laboratories of Ma...
Rockefeller, with four other institutions, to receive $100 million cancer research grant
The Starr Foundation, a philanthropic organization that supports education, medicine and healthcare, as well as cultural institutions, human needs, public policy and the environment, announced today that it has made a $100 million grant to create a wide-ranging cancer consortium to coordinate the...
A wolf in sheep's clothing: plague bacteria reveal one of their virulence tricks
The bacterium that causes the plague belongs to a virulent family of bacteria called Yersinia, a group that also includes a pathogen responsible for food poisoning. These bacteria insert into their host cells proteins and other virulence factors, which kill by — among other things — disrupting ...
Phosphorylation of WAVE1 protein remodels neuronal connections
Paper marks 50th anniversary of Paul Greengard's first publication in journal Nature.  Within the brain, branched nerve cell extensions called dendrites play a key role in how cells communicate with one another by sending electrical signals from the tip of one neuron to the tip of the next – a p...
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