Laboratory of Molecular Pathogenesis

The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors.

Findings bolster the idea that the functions of this protein—MeCP2—are more centered on nucleosomes, rather than other forms of DNA.