Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease’s symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
Scientists developed a method to genetically engineer gut bacteria to produce molecules that have the potential to treat certain disorders by altering human metabolism.
In the rats that roam New York City’s streets and tunnels, scientists have found a virus that resembles hepatitis C. They have used it to create the first animal model of the human disease, a breakthrough that potentially could yield a much-needed vaccine.
Allis has received the March of Dimes Prize in Developmental Biology. The award, given to investigators whose research offers hope for the prevention and treatment of birth defects and other infant diseases, honors Allis for his groundbreaking work on gene regulation.