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Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.

Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.

Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.

Sohail Tavazoie, a physician-scientist who studies the genes that regulate a tumor’s ability to metastasize, has been promoted to professor.

A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.

After figuring out the functions of two proteins involved in the rare genetic condition ICF, scientists pieced together the molecular process that is altered in the disease.

A new treatment may help cancer patients who don't respond to traditional immunotherapy. Findings from the first-ever clinical trial reveal that it is effective in activating immune cells that kill cancer cells.

Researchers discovered how apoptosis keeps potential cancer-causing mutations in check.

With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.