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Displaying 176 of 2907 articles.
Scientists capture the moving parts of the portal to the cell’s nucleus
The proteins of the nuclear pore complex flip-flop rapidly between two orientations as they let cargo through.
As COVID-19 vaccines emerge, the search for antiviral drugs continues
Scientists are digging through drug libraries of 430,000 compounds, in pursuit of an antiviral drug that can stop the novel coronavirus in its tracks.
Telomere shortening protects against cancer
Researchers have found the first evidence that telomere shortening is not just a sign of aging, but a key component of the body's cancer prevention system.
New atlas reveals the journey of human cells throughout development
The largest map of gene expression in over 4 million human cells charts the dynamic path to forming different organs.
How cells use mechanical tension sensors to interact with their environment
In a painstaking experiment, scientists suspended a single protein filament between two microscopic beads. Their results have shed light on an elusive process in which cells receive and respond to mechanical cues.
Rockefeller's Charles M. Rice honored with Nobel Prize for research that contributed to a cure for hepatitis C
Rice will receive the 2020 Nobel Prize in Physiology or Medicine for research that led to a cure for hepatitis C, a viral disease affecting 170 million people worldwide. His lab worked on the virus for three decades and became the first to produce a version of it that could be grown and studied i...
How dividing cells avoid setting off false virus alarms
A new molecular structure explains how cells hold an alarm-triggering protein captive during cell division, preventing cells from targeting their own DNA.
How mechanical forces nudge tumors toward malignancy
Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the di...
Will SARS-CoV-2 escape future drugs by mutating? The answer may be a nuanced “no.”

Scientists hope to deploy antibodies in the quest to end COVID-19. A recent study moves them closer to accomplishing a key step: finding out if the virus may acquire resistance to antibody-based drugs or vaccines, and how to potent...

How toothless mock viruses could advance research on COVID-19
Scientists have engineered four viruses resembling SARS-CoV-2 to enable faster and safer research on vaccines and treatments.
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