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Displaying 175 of 2889 articles.
Newly-developed molecules bind to a key enzyme pocket to inhibit its activity, and possibly prevent autoimmune responses.
Science News

New compounds could be used to treat autoimmune disorders

In autoimmune disorders, the body’s defense system erroneously attacks normal cells, leading to serious health problems. Researchers have developed new molecules that potentially could be used to treat many of these conditions.
Here, a winner (red) engulfs a loser (green)
Science News

Cellular rivalry promotes healthy skin development

Scientists have discovered a curious phenomenon taking place in mouse skin: cells compete with one another for the chance to develop into mature tissue. The findings indicate that this antagonism is key to creating healthy skin.
Human astrocytes
Science News

Research on repetitive worm behavior may have implications for understanding human disease

Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.
Tumor stem cells
Science News

Study pinpoints what causes relapse after cancer immunotherapy

In many cancer patients who have been treated with immunotherapy, the tumor comes back. New research identifies the cells responsible for thwarting the treatment and offers new insights into how they do it.
DIPG cells, pictured here, are generally resilient and replicate rapidly. With a dose of MI-2, however, the cells abruptly die.
Science News

New hope for treating a childhood brain cancer

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.
Intestine
Science News

New approach to treating gastrointestinal disease patches up leaky intestines

Researchers have discovered a new compound that helps fortify the intestine's inner lining, which becomes porous in inflammatory bowel diseases.  
Science News
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In Brief

Researchers discover a common link among diverse cancer types

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.
Science News
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In Brief

Scientists find new clues about how the body stores fat

Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.
An excess of squalene (pink)—
Science News

Researchers discover a weakness in a rare cancer that could be exploited with drugs

Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.
Jeff Friedman
Awards and Honors, Campus News

Jeffrey M. Friedman to receive the 2019 Wolf Prize in Medicine

Friedman receives the award for his discovery of leptin, a hormone that modulates food intake and energy expenditure.
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