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DIPG cells, pictured here, are generally resilient and replicate rapidly. With a dose of MI-2, however, the cells abruptly die.
Science News

New hope for treating a childhood brain cancer

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.
Activation of hD2R neurons
Science News

Scientists find brain mechanism that naturally combats overeating

Studying a brain region involved in memory, researchers discovered a set of neurons that help mice control their appetite.
Science News
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In Brief

Researchers discover a common link among diverse cancer types

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.
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In Brief

Scientists find new clues about how the body stores fat

Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.
Leptin mouse
Science News

Scientists identify genetic factors that may cause some people to become obese

New research on leptin, a hormone that regulates appetite, reveals a previously unknown mechanism that may be responsible for at least 10 percent of obesity cases. The findings could help identify individuals with treatable forms of the condition.
C. elegans
Science News

Inside the brains of hungry worms, researchers find clues about how they hunt

When looking for food, the roundworm C. elegans searches the same area for up to 20 minutes before trying its luck at more distant locales. New research on the worm’s brain explains how this behavior arises at the level of molecules and cells.
An excess of squalene (pink)—
Science News

Researchers discover a weakness in a rare cancer that could be exploited with drugs

Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.
Mosquitos illustration
Science News

New findings could make mosquitoes more satisfied—and safer to be around

Scientists have learned new tricks that could be useful in preventing mosquito-borne illnesses such as Zika and yellow fever. A new study shows that some appetite-reducing drugs can curtail the insects’ impulse to feed on warm-blooded hosts.
Jeff Friedman
Awards and Honors, Campus News

Jeffrey M. Friedman to receive the 2019 Wolf Prize in Medicine

Friedman receives the award for his discovery of leptin, a hormone that modulates food intake and energy expenditure.
Geckos move through water they slap their arms, generating air bubbles that help them stay afloat.
Science News

Study explains how geckos gracefully gallop on water

Geckos are amazingly agile. In addition to running across land and up trees, the animals can prance across the surface of water. A new study reveals how they do it.
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