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Genomic testing could speed research on skin disease and bring new drugs to patients faster
In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them. Unfortunately, in the real world, it can take several months to determine whether a given patient will respond to one of these medications, which target specif...
Rockefeller graduate Monica Mugnier wins 2016 NIH Early Independence Award
Monica Mugnier, who completed her Ph.D. at Rockefeller earlier this year, is one of 16 junior investigators nationwide to receive a National Institutes of Health Director’s Early Independence Award. The award, which is part of the NIH’s High-Risk, High-Reward Research program, allows early-caree...
Study explains how an intestinal microbe protects against other, more dangerous bacteria
Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside. Probiotics consisting of beneficial microorganisms, meanwhile, have the potential to delive...
Four Rockefeller scientists named 2016 HHMI Faculty Scholars
Four Rockefeller University scientists—Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie—have been named Howard Hughes Medical Institute Faculty Scholars. The Faculty Scholars program, a new collaboration between HHMI, the Simons Foundation, and the Bill & Melinda Gate...
Scientists uncover a clever ranking strategy bacteria use to fight off viruses
Like humans, bacteria come under attack from viruses and rely on an immune system to defend themselves. A bacterial immune system known as CRISPR helps microbes “remember” the viruses they encounter and more easily fend them off in the future. Since researchers first discovered CRISPR in the mid...
Charles M. Rice wins Lasker Award for groundbreaking work on the hepatitis C virus
Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology and head of the Laboratory of Virology and Infectious Disease, has been honored with the 2016 Lasker-DeBakey Clinical Medical Research Award, the country’s most prestigious science prize. Rice shares the award with Ralf F....
Daniel Mucida, who studies the gut’s specialized immune system, receives promotion
by Wynne Parry, science writer As of September 1, Daniel Mucida, who heads the Laboratory of Mucosal Immunology and studies the immune system along the vast surface of the intestine, will become an associate professor. The Board of Trustees approved his promotion on July 29. Although hidd...
New antibody drug continues to show promise for treatment of HIV
Great strides have been made in recent years to develop treatment options for HIV, and the disease can now be controlled with anti-retroviral drugs. But a cure remains elusive and current medications have limitations: they must be taken daily, for life, and can cause long-term complications. Now,...
Resistance to antidepressants linked to metabolism
Often, clinical depression has company; it shows up in the brain alongside metabolic abnormalities, such as elevated blood sugar, in the body. While studying an experimental antidepressant in rats, Rockefeller University researchers and their colleagues at Karolinska Institutet in Sweden found so...
An unexpected origin for calming immune cells in the gut
Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection—and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells. The immune...
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