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Displaying 175 of 2907 articles.
Study uncovers the molecular events by which popular antidepressants work
Scientists have outlined a molecular program by which serotonin reuptake inhibitors reshape the brain to alleviate depression. Their findings provide clues for how to make better and faster-acting versions of these drugs.
How neurons in body fat grow to boost calorie-burning capacity
Scientists have found that a hormone tells the brain to dramatically restructure neurons embedded in fat tissue.  Their work widens our understanding of how the body regulates its energy consumption, and how obesity might be treated in the future.
Why memory-forming neurons are vulnerable to Alzheimer's
Scientists have used advanced technology to “micro-dissect” the first brain cells to perish in Alzheimer’s disease. The result is a short list of genes that could represent new drug targets.
Transparent fish reveal the subtle, cellular dance in which sensory organs take shape
How do primitive cells “know” where to go during development? Scientists studying the fish equivalent of inner-ear hair cells have shown that biochemical and mechanical cues work together to orchestrate a highly complex arrangement.
Brain study finds a molecular “off” switch for nicotine craving
In findings that might lead to better smoking-cessation tools, scientists have shown that manipulating a specific brain receptor can alter a mouse’s nicotine sensitivity.
How decisions unfold in a zebrafish brain
Tracking neuronal activity in a zebrafish brain, researchers can predict when the fish will flip its tail and to which direction, left or right.
A surprising new source of attention in the brain
Scientists find a new brain area in control of our attention skills, raising new questions in what has long been considered a settled scientific field.
Scientists develop new method that predicts vulnerability to stress
Researchers have identified a set of biological factors in mice that seem to determine one's ability to bounce back from a traumatic event, and provide preliminary evidence that a naturally-occurring substance may help boost resiliency in the face of stressful situations.
Neurodegenerative diseases may be caused by molecular transportation failures inside neurons
Protein clumps are routinely found in the brains of patients with neurodegenerative diseases. Now researchers find a link between this buildup and the intracellular movement of proteasomes, molecular machines tasked with degrading protein waste inside cells.
The pathway to Parkinson’s takes a surprising twist
A new study finds that neurons affected in Parkinson’s disease can shut down without fully dying, allowing them to also switch off neighboring cells. The findings might give scientists a better understanding of how the condition wreaks havoc in the brain, as well as ideas for new treatments.
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