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Science News

Proteins that transport cholesterol identified

Structural data reveals key aspects of function Professor Jan Breslow and colleagues, including biomedical fellow Raymond Soccio, recently discovered a novel subfamily of the START domain lipid transfer proteins, which are thought to shuttle lipids such as cholesterol within cells. In addition, ...
Science News

Researchers Solve Killer Protein's "Crime"

A killer protein named Reaper. A protective protein in bits and pieces. And a dead cell. This is the scene of one of the body's most perfect crimes: programmed cell death. This vital process occurs throughout life as a means to, among other purposes, eliminate potentially cancerous cells. Now, by...
Awards and Honors

"Vanishing Breed" of Researchers Recognized by HHMI

One clinical scientist selected in New York region: Rockefeller's Robert Darnell Robert B. Darnell, M.D., Ph.D., whose bench-to-bedside studies at Rockefeller University have uncovered new insights about how the brain normally works and about tumor immunity, is one of the 12 physician-scientists ...
Science News

The making of a fat cell

Researchers identify a key ingredient in development of body fat The future of a young body cell is filled with uncertainties. Will it mature into a red blood cell and carry oxygen to remote tissues? Or might it become a liver cell and help rid the body of dangerous toxins? Ultimately, its destin...
Science News

Three-D images shed light on first steps of RNA synthesis

The first three-dimensional images of the initiating form of the molecular machinery in bacteria that "transcribes" genetic information from DNA into RNA — the crucial first step for making proteins — is reported in a pair of papers in the May 17 issue of the journal Science. These research fin...
Science News

More Than Just Packaging, Histones Help Turn Genes On

Rockefeller scientists redefine role of proteins responsible for bundling DNA into cells Histones, the proteins that help roll several feet of DNA into the microscopic span of a single nucleus, are turning out to be much more than just packaging material. Instead, recent studies indicate that the...
Science News

"Good Citizens" in the Immune System Carry Out State's Orders

Diversity in PKC signaling enzymes yields clues to tolerance The difference between good and evil matters as much in the immune system, it turns out, as it does to humankind. The problem is understanding how the immune system's cells perceive the difference. In the April 25 issue of the journal N...
Science News

Leprosy bug provides clues to early nerve degeneration

Possible insight to multiple sclerosis and other neurodegenerative diseases that destroy nerve cell "insulation" In the May 3 issue of Science, scientists at Rockefeller University and New York University School of Medicine report that the nerve damage that leads to a loss of sensation and disab...
Science News

Nature's Own Antidote to Cocaine

Brain opiate may explain why some people are less susceptible to addiction Some people's brains may harbor their own built-in defense system against the addictive powers of cocaine. According to new research at The Rockefeller University, a naturally occurring brain opiate called dynorphin may, i...
Campus News

Rockefeller University Announces Scholarship Fund in Name of Employee Who Died at World Trade Center

Shaheed Mohammed Salman Hamdani Memorial Fund will benefit Pakastani-American Students Rockefeller University's Acting President Thomas P. Sakmar, M.D., announced today the establishment of the Shaheed Mohammed Salman Hamdani Memorial Fund, named for the 23-year-old research technician who died w...
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