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New science of "epigenetics" advanced by findings reported in Molecular Cell

New science of "epigenetics" — which explores how physical characteristics of cells and their chromosomes can be inherited separate from the DNA sequence — is advanced by recent findings reported in Molecular Cell Since Gregor Mendel first crossed strains of peas in his garden over 100 years ag...

New method identifying and isolating stem cells developed

Cells may help researchers in skin and hair therapies; tool can be used to find other body stem cells, including cancer stem cells Researchers at the Howard Hughes Medical Institute at The Rockefeller University have discovered a new method to track and isolate elusive stem cells. The new animal ...

Trial of new investigational AIDS vaccine begins in New York and Rochester

Healthy Volunteers Sought for New AIDS Vaccine Research Effort The Aaron Diamond AIDS Research Center (ADARC), an affiliate of The Rockefeller University, and the International AIDS Vaccine Initiative (IAVI) announced today that they have begun a human trial of a new investigational vaccine to pr...

Genes may protect against heart disease rather than be harmful as previously thought

A genetic pathway whose activity was suspected to advance heart disease by increasing inflammation in the blood vessels and arteries feeding the heart may actually protect against it at least in laboratory mice, reports a team of Rockefeller University scientists led by Jan Breslow, M.D., in the ...

Mouse studies show brain's "master molecule" produces same behavior from three different psychostimulant drugs

Findings may lead to new drug targets for treating schizophrenia A mouse study reported in this week's Science magazine shows that three drugs, each acting on a different chemical transmitter in the brain, all produce the same schizophrenia-like symptoms by acting on a single "master molecule" in...

By the year 2050, human population could add 2.6 billion people, reports Rockefeller scientist Joel E. Cohen

It took from the beginning of time until 1950 to put the first 2.5 billion people on the planet. Yet in the next half-century, an increase that exceeds the total population of the world in 1950 will occur. So writes Joel E. Cohen, Ph.D., Dr.P.H., professor and head of the Laboratory of Population...

Researchers describe new technique for cataloging RNA targets in rare brain disease

CLIP-ping the messenger In journal Science, researchers describe new technique for cataloging RNA targets in rare brain disease New method may apply to diseases such as Fragile X mental retardation RNA, often thought of as merely the chemical messenger that helps decode DNA's genetic instructions...

Giant protein organizes the transportation railway system within cells

To get its job done, each cell in the human body must constantly change its inner skeleton and therefore its outer shape. This skeleton also serves as a vast network of "tracks," which grow and shrink and move in different directions as needed to transport proteins and other materials within the ...

GenSAT (Gene Expression Nervous System Atlas) Project announced

Unprecedented genetic access to brain provided by Rockefeller University scientists For scientists studying the brain, this week's Nature announces a remarkable new map describing previously uncharted territory, plus the means of exploring the new horizons for themselves. Rockefeller University s...

"Gene therapy" in worms identifies protein that plays role in controlling water balance, sense of touch in live animals

Using "knockout" mice and mutant roundworms, researchers at The Rockefeller University and the University of California, San Francisco, have identified a protein that helps control water balance in the body and underlies the sensation of touch — functions basic to life that have long eluded expla...