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Science News

Growth signal can influence cancer cells’ vulnerability to drugs, study suggests

In theory, a tumor is an army of clones, made up of many copies of the original cancerous cell. But tumor cells don’t always act like duplicates, and their unpredictable behavior can create problems for treatment. For while some cells within a tumor succumb to anti-cancer drugs, others may surviv...
Science News

Research captures transient details of HIV genome packaging

Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly process falls to a viral protein known as Gag. For one thing, Gag must be able to discern viral RNA...
Science News

Virus-cutting enzyme helps bacteria remember a threat

Bacteria may not have brains, but they do have memories, at least when it comes to viruses that attack them. Many bacteria have a molecular immune system which allows these microbes to capture and retain pieces of viral DNA that they have encountered in the past, in order to recognize and destroy...
Science News

Key to blocking influenza virus may lie in a cell’s own machinery

Viruses are masters of outsourcing, entrusting their fundamental function – reproduction – to the host cells they infect. But it turns out this highly economical approach also creates vulnerability. Researchers at Rockefeller University and their collaborators have found an unexpected way the...
Science News

Drug-resistant bacteria lurk in subway stations, high school students discover

Forget the five-million plus commuters and untold number of rats – many of the living things crowded into the New York City subway system are too small to see. An interest in the more menacing among these microbes led high school student Anya Dunaif, a participant in Rockefeller’s Summer Science...
Science News

Latent HIV may lurk in ‘quiet’ immune cells, research suggests

Drugs for HIV have become adept at suppressing infection, but they still can’t eliminate it. That’s because the medication in these pills doesn’t touch the virus’ hidden reserves, which lie dormant within infected white blood cells. Unlock the secrets of this pool of latent virus, scientists...
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Research implicates metabolic process of the liver in the spread of colorectal cancer

Colorectal cancer is a cancer on the move: about 50 percent of patients with the disease see their cancer spread, typically to the liver. By identifying genes that become activated in cancer cells that successfully travel — metastasize — to the liver, researchers at Rockefeller have implicated...
Science News

Study detailing axonal death pathway may provide drug targets for neurodegenerative diseases

Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer’s or Parkinson’s disease, axonal degenerati...
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Long-acting drug effectively prevents HIV-like infection in monkeys

A regime of anti-HIV drugs — components of regimens to treat established HIV infection — has the potential to protect against infection in the first place. But real life can interfere; the effectiveness of this prophylactic approach declines if the medications aren’t taken as prescribed. ...
Science News

Facial motion activates a dedicated network within the brain, research shows

A face is more than a static collection of features. A shift in gaze, a tightening of the lips, a tilt of the head, these movements convey important clues to someone’s state of mind. Scientists know that two particularly social and visual creatures, humans and rhesus macaque monkeys, have a netwo...
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