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Science News

Discovery of pro-metastasis protein reveals mysterious link to neurodegeneration

Researchers have identified a protein that makes breast cancer cells more likely to metastasize. What's more, the protein appears to trigger cancer's spread in part by blocking two other proteins normally linked to neurodegeneration, a finding that suggests a tie between two of the most common di...
Science News

Researchers create the first model of the DNA ‘replication fork’

Human cells make new copies of their DNA billions of times each day, a crucial process upon which life itself depends. However, scientists do not fully understand how cells unzip the double-stranded DNA molecule before replicating both halves of it. New work at Rockefeller may help change that. F...
Science News

Genetically driven gut feelings help female flies choose a mate

Even among flies, mating is a complicated ritual. Their elaborate, and entirely innate, courtship dance combines multiple motor skills with advanced sensory cues. Now, researchers at Rockefeller University have determined that the Abdominal-B (Abd-B) gene, previously known as the gene that sculpt...
Science News

Using geometry, researchers coax human embryonic stem cells to organize themselves

About seven days after conception, something remarkable occurs in the clump of cells that will eventually become a new human being. They start to specialize. They take on characteristics that begin to hint at their ultimate fate as part of the skin, brain, muscle or any of the roughly 200 cell ty...
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Potential Alzheimer’s drug prevents abnormal blood clots in the brain

Without a steady supply of blood, neurons can’t work. That’s why one of the culprits behind Alzheimer’s disease is believed to be the persistent blood clots that often form in the brains of Alzheimer’s patients, contributing to the condition’s hallmark memory loss, confusion and cognitive ...
Science News

Sequencing efforts miss DNA crucial to bacteria’s disease causing power

Genomic sequencing is supposed to reveal the entire genetic makeup of an organism. For infectious disease specialists, the technology can be used to analyze a disease-causing bacterium to determine how much harm it is capable of causing and whether or not it will be resistant to antibiotics. But ...
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New monkey model for AIDS offers promise for medical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees. While this would qualify as good news for most mammals, for humans this fact has made the search for effective treatments and vac...
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To recover consciousness, brain activity passes through newly detected states

Anesthesia makes otherwise painful procedures possible by derailing a conscious brain, rendering it incapable of sensing or responding to a surgeon’s knife. But little research exists on what happens when the drugs wear off. “I always found it remarkable that someone can recover from anesthesia...
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Research details how developing neurons sense a chemical cue

Symmetry is an inherent part of development. As an embryo, an organism’s brain and spinal cord, like the rest of its body, organize themselves into left and right halves as they grow. But a certain set of nerve cells do something unusual: they cross from one side to the other. New research in mic...
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Researchers profile active genes in neurons based on connections

When it comes to the brain, wiring isn’t everything. Although neurobiologists often talk in electrical metaphors, the reality is that the brain is not nearly as simple as a series of wires and circuits. Unlike their copper counterparts, neurons can behave differently depending on the situation. R...
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