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Newly discovered deep sea lobster named for Rockefeller’s Jesse Ausubel

Some scientists receive prizes for their contributions to science, others find themselves on postage stamps. Rockefeller University’s Jesse Ausubel name is now immortalized in the scientific name of a newly discovered, rare new genus of deep water lobster. Ausubel was given this honor as a tribut...

New research traces evolutionary path of multidrug resistant strep bacteria

Despite penicillin and the dozens of antibiotics that followed it, streptococcus bacteria have remained a major threat to health throughout the world. The reason: the superb evolutionary skills of this pathogen to rapidly alter its genetic makeup. In a landmark paper published this week in Scienc...

Research shows when stem cell descendants lose their versatility

Stem cells are the incomparably versatile progenitors of every cell in our body. Some maintain this remarkable plasticity throughout the life of an animal, prepared to respond as needed to repair an injury, for instance. Others differentiate into specialized cells, regenerating tissue or facilita...

Scientists identify protein that drives survival of gastrointestinal tumors

Scientists identify protein that drives survival of gastrointestinal tumors For patients with gastrointestinal stromal tumors, or GISTs, the blockbuster cancer drug Gleevec has been a reason to hope. Since the drug’s introduction, survival rates have climbed dramatically and recurrence has fal...

Studies describe key role for a protein in cell division

Just before a cell divides into two — the basic act of reproducing life — the cellular environment must be exquisitely prepared. The exact timing and localization of the vast array of molecules and processes involved in duplicating chromosomes and separating the offspring from the parent is one ...

Therapy for fearsome brain disease could target blood

The aggregated proteins strewn about a deranged brain are the hallmark of one of the most feared and common neurodegenerative disorders on the planet: Alzheimer’s disease. But while these irregular, gunky proteins, called amyloid-β, are believed to contribute to the deterioration of memory and co...

Paleovirology expanded: New virus fragments found in animal genomes

Understanding the evolution of a virus can help beat it. This is immediately true in the fight against the ever-changing influenza bug, and potentially so in ongoing battles against Ebola and dengue fever, too. New research now points the way to a fossil record of viruses that have surprisingly i...

New class of ‘dancing’ dendritic cells derived from blood monocytes

Dendritic cells, known to be the prime movers of the body’s immune response, are still notoriously difficult to study in humans. Samples, which come primarily from bone marrow or lymphoid tissue, are simply too difficult to obtain. But new research at Rockefeller University has shown scientists a...

‘Reaper’ protein strikes at mitochondria to kill cells

Our cells live ever on the verge of suicide, requiring the close attention of a team of molecules to prevent the cells from pulling the trigger. This self-destructive tendency can be a very good thing, as when dangerous precancerous cells are permitted to kill themselves, but it can also go horri...

New faculty member wants to know how flies make decisions

Fruit flies are not known for their sense of direction. Even among animals with tiny brains, they are particularly prone to sudden, sharp changes of direction and circuitous navigation. But their abrupt movements are not accidental. Understanding how they decide when to veer right or left is imp...