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Rockefeller University receives nearly $27 million in ARRA grants

Investigators at The Rockefeller University have so far been awarded 41 federal grants and supplemental awards through the American Recovery and Reinvestment Act of 2009 (ARRA) — the so-called “stimulus” legislation passed by Congress last winter. The awards — 40 from the National Institutes...

Mutation leads to new and severe form of bacterial disease

Fighting an illness is not just about fighting the bacteria or viruses that cause it, it also has to do with your genes. In new research from Rockefeller University and the Necker Medical School in Paris, scientists have identified a gene mutation that makes children susceptible to a severe form ...

Bacterial protein mimics its host to disable a key enzyme

Helicobacter pylori infects up to 90 percent of people in the developing world and causes gastric ulcers and cancers of the gut. Now scientists have revealed a subterfuge used by the bacterium to trick stomach cells into playing along. By injecting a protein into the stomach lining that mimics a ...

New molecule identified in DNA damage response

In the harsh judgment of natural selection, the ultimate measure of success is reproduction. So it’s no surprise that life spends lavish resources on this feat, whether in the courtship behavior of birds and bees or replicating the cells that keep them alive. Now research has identified a new pie...

Elusive protein points to mechanism behind hearing loss

A serendipitous discovery of deaf zebra fish larvae has helped narrow down the function of an elusive protein necessary for hearing and balance. The work, led by Rockefeller University’s A. James Hudspeth, suggests that hearing loss may arise from a faulty pathway that translates sound waves into...

Rockefeller human embryonic stem cell lines now available through NIH registry

Two human embryonic stem cell lines, derived by Rockefeller University scientists, are among the first 13 human embryonic stem cell lines for use in research funded by the National Institutes of Health under the NIH Guidelines for Human Stem Cell Research adopted in July 2009. The two lines, call...

Acute stress leaves epigenetic marks on the hippocampus

In trying to explain psychiatric disorders, genes simply cannot tell the whole story. The real answers are in the interaction of genes and the environment. Post-traumatic stress disorder requires some trauma, for instance, and people, for the most part, aren’t born depressed. Now research has rev...

Scientists identify DNA that regulates antibody production

Performance enhancers are the currency of a competitive society. But there’s one that we have always had: For millions of years, segments of our DNA have improved the performance of our genome, revving up protein production at those times we need it most. New research from Rockefeller University ...

Multitasking may be Achilles heel for hepatitis C

Despite its tiny genome, the hepatitis C virus packs a mean punch. The virus is a microcosm of efficiency, and each of its amino acids plays multiple roles in its survival and ability to sidestep attack. But new research from Rockefeller University suggests that this fancy footwork and multitaski...

Imaging study shows HIV particles assembling around its genome

HIV is a wily and lethal replicator. In less than 25 years, it’s killed more than 25 million people. Scientists are exploring exactly how this virus reproduces because they would like to find a way to abort the process. Now, just two years after a group at Rockefeller University was the first to ...