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Science News

Simulator allows scientists to predict evolution's next best move

Biologists today are doing what Darwin thought impossible. They are studying the process of evolution not through fossils but directly, as it is happening. Now, by modeling the steps evolution takes to build, from scratch, an adaptive biochemical network, biophysicists Eric D. Siggia and Paul Fra...
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Plant virus spreads by making life easy for crop pests

In 752, Japanese Empress Koken wrote a short poem about the summertime yellowing of a field in what is thought to be the first account of a viral plant disease. More than 1,250 years later, scientists concluded that the virus Koken described was part of the particularly insidious geminivirus fami...
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In mice, anxiety is linked to immune system

In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia Universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations. The work, to appear ...
Science News

Scientists discover how a well-known protein repairs broken DNA ends

During the life cycle of our cells, a minefield of environmental and biological assaults can lead to double-stranded DNA breaks, the most lethal and dangerous form of DNA damage. Now, in research published online this week inNature, Rockefeller University scientists reveal that when these breaks ...
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A new role for a critical DNA molecule in the immune system

The human immune system is a brilliantly adaptable weapon against foreign invaders. But it all depends on the work of specialized cells called lymphocytes that have made a risky evolutionary gambit to mutate their own DNA. New research to be published this week in Nature shows for the first time ...
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By recognizing odors, a single neuron controls reactions

“When you’re out hiking, you’ll notice that everything tastes really delicious. That’s one of the best parts about hiking, actually, is how delicious a peanut butter and raisin sandwich can be,” says Cori Bargmann, Torsten N. Wiesel Professor and head of the Laboratory of Neural Circuits a...
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Molecule stops DNA replication in its tracks

The process is akin to unzipping a zipper: The sliding clamp works its way along the DNA double helix while a network of proteins work together to unwind the two strands. Proteins known as polymerases then add, in assembly-line fashion, nucleotide bases — the building blocks that make up DNA — t...
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Study specifies chemical pathways for ions through cell membrane

Life ultimately depends on the traffic of tiny charged particles through porous proteins studding the membrane surrounding every cell. In research published in Nature, scientists at The Rockefeller University have for the first time mapped a stepping-stone pathway of amino acids that these charge...
Science News

Newly identified cells make fat

To understand where fat comes from, you have to start with a skinny mouse. By using such a creature and observing the growth of fat after injections of different kinds of immature cells, Rockefeller University scientists have discovered an important fat precursor cell that may in time explain how...
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Scientists identify a molecule that coordinates the movements of cells

Even cells commute. To get from their birthplace to their work site, they sequentially attach to and detach from an elaborate track of exceptionally strong proteins known as the extracellular matrix. Now, in research to appear in the October 3 issue of Cell, scientists at Rockefeller University s...
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