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Displaying 1189 of 2890 articles.

From cell to gel: refined protocol uses GFP to locate proteins and examine their interactions

There are two things cell biologists always want to know: where is their protein found and what other proteins does it associate with. A new protocol has been developed at the Rockefeller University that will enable scientists to answer both in one fell swoop. One of the most common ways scientis...

Neurons in the brain change shape when stressed

Long-term stress, like the kind that occurs when someone cares for a chronically ill parent or spouse, can impair short-term memory. Researchers believe that this occurs because constant stress affects an area of the brain necessary for learning and memory, and the underlying mechanisms for this ...

Immune cell receptors act in combination to regulate attack

The complexities of the mammalian immune system allow our bodies to fend off countless diseases. But researchers are still working to pin down exactly how it works — and to understand why some people’s antibodies, and some therapeutic antibodies, are better able to fight off disease than others...

Scientists say toxins use their shape to wreak havoc on cells

Last year, Rockefeller University scientists used X-ray crystallography to determine the structure of cytolethal distending toxin (or CDT) — a widespread toxin found in diverse, disease-causing bacteria that binds to human cells, inserts a component of itself inside, then proceeds to attack the c...

Building a better vaccine

Rockefeller’s Charlie Rice thinks that scientists struggling to create a vaccine to protect against the widely predicted avian flu pandemic might learn a thing or two from yellow fever. “The yellow fever 17D vaccine is one of the most successful vaccines ever created,” says Rice, the Maurice ...

From primordial soup to cells

Life is complicated. Even the simplest cell has to deal with continual changes in temperature, pressure, food, and anything else the environment wants to throw at it. After millions of years adapting to every kind of condition, it is hard to determine what genes are actually driving the cell and ...

New report bolsters theory on ear's inner amplifier

Seven years ago, A. James Hudspeth, head of Rockefeller’s Laboratory of Sensory Neuroscience, proposed a new theory for the workings of the inner ear. In research published last week in the online Early Edition of the Proceedings of the National Academy of Sciences, Hudspeth bolsters his theory b...

Reversing sugar's effect on the brain

The estimated 1 million people in the United States with type 1 diabetes know that uncontrolled high blood sugar can attack the body’s organs. New research from Rockefeller University’s Bruce McEwen and colleagues at the University of South Carolina shows that the brain is one target of the dise...

Scientists teach worms to learn

Thanks to their simple 302-cell nervous system, the worm is a great model for biologists studying how brain cells work. Unfortunately, worms are not known for their memory. So when Rockefeller University’s Cori Bargmann wanted to study how worms can form memories based on odors, she first needed ...

Application deadline for faculty search is next week

Scientists interested in tenure-track faculty positions in the biological and biomedical sciences at The Rockefeller University must submit applications by November 15. The university is recruiting candidates at the assistant professor level who are in the early stages of their scientific careers...