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Displaying 1189 of 2890 articles.

In flies, odorant receptors work together

Locating a bruised, three-day-old banana takes a keen sense of smell. Yet fruit flies have just 62 different odorant receptors – compared to a thousand or more that exist in humans. A new paper published this week by Rockefeller University researchers Leslie Vosshall and Elane Fishilevich shows h...

New gene in Fanconi anemia "explains" hallmark chromosomal instability

Surprising findings from just five patients has led to the first proof of how the rare disorder Fanconi anemia causes chromosomal instability. A team of international researchers, led by scientists at Rockefeller University, reports the findings in the September issue of Nature Genetics. The scie...

Rockefeller researchers show evidence of asymmetric cell division in mammalian skin

It took almost 10 years for Elaine Fuchs, Ph.D., a Howard Hughes Medical Institute investigator at Rockefeller University, to find a postdoctoral fellow who shared her curiosity for the direction of cell divisions in the skin. Then Terry Lechler, Ph.D., came along and the result is a new paper pu...

Never too much of a good thing

Changing levels of a single protein can produce many different outcomes An ongoing scientific argument surrounds the Wnt protein: Different research groups say that Wnt proteins are involved in cell differentiation, proliferation, fate determination, stem cell self-renewal and cancer. But which g...

Single stressful events bring about gradual change in brain structure

Commuting is never fun, and is almost always stressful, in part because we often have no control over what happens to us. But everyday we get in our car, or board the train or bus, and make our way to work, having become accustomed to this stress, not realizing that this stress may have a measura...

Protein destruction helps plants enter a different life stage

As a seed awakens and begins to sprout, it must make a decision: does it have everything it needs to grow, or should it wait for better conditions? The choice rests on the presence or absence of one protein, ABI3, and new research from the laboratory of Nam-Hai Chua, Ph.D., at Rockefeller Univers...

Size doesn't matter

Rockefeller scientists show that microRNAs play an essential role in the development of the fruit fly In a story reminiscent of David and Goliath, new research from Rockefeller University shows that sometimes the smallest molecules can be the most powerful. In the July 1 issue of Cell, Ulrike Gau...

Researchers create infectious hepatitis C virus in a test tube

Method enables scientists to study all stages of virus' life cycle A team of researchers led by scientists at The Rockefeller University has produced for the first time an infectious form of the hepatitis C virus (HCV) in laboratory cultures of human cells. The finding, reported in the June 9 iss...

Worming our way into the brain

Rockefeller scientists find that studying glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases. The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June is...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

Naturally replaced neurons may hold the key to understanding processes of neurodegeneration In certain parts of the brain, cells called neurons go through a cycle of death and replenishment. New research from Rockefeller University's Fernando Nottebohm, Ph.D., shows that these replaceable neurons...