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Researchers uncover a pathway linked to autoimmune disease

When a person’s immune cells lose the ability to distinguish “self” from “non-self,” they end up launching an attack on the body they’re supposed to protect. Exactly what happens to rob them of that ability has been the subject of decades of research. In a series of discoveries that has ...
Science News

Lizard's 'third eye' sheds light on how vision evolved

A primitive third eye found in many types of lizards, used to detect changes in light and dark and to regulate the production of certain hormones, may help explain how vision evolved and how signals are transmitted from the eyes to the brain, according to new research by Rockefeller University sc...
Science News

Researchers show laboratory hepatitis C strain is also infections in animal models

An important step in developing a treatment for viral diseases is for scientists to culture live viruses from infected patients, but the hepatitis C virus (HCV), a major cause of chronic and sometimes fatal liver disease, has proven to be particularly wily. For many years scientists have struggle...
Science News

Paul Nurse to co-host Charlie Rose on avian flu

Rockefeller President Paul Nurse will make his second appearance on Charlie Rose tonight, when he co-hosts, with Rose, an hour-long discussion on the threat of avian flu. The show, which is to be the first in a series of science-themed Charlie Rose shows co-hosted with Nurse, will air on PBS tele...
Science News

When mice choose mates, experience counts

Choosing a mate is a big decision. And, at least for mice, it’s one that is best made with input from one’s peers. In a series of experiments designed to help scientists understand the brain chemicals that guide mate selection, Don Pfaff and his colleagues exposed female mice to the odor of eit...
Science News

Developing neurons reverse direction in absence of Wnt protein

There are 10 billion neurons in the human brain, with 10 trillion connections, and in this complex web, every bit of information must be routed along the correct path. But despite years of study, scientists don’t fully understand how the body forms the neural pathways that route that information....
Science News

Aggravated assault: How adhesion proteins regulate skin inflammation

When it comes to skin, the tighter the better. To create an effective barrier, cells in the epidermal, or outermost, layer of the skin form very tight associations. But while strong links between skin cells protect the body from the world outside, new research from Rockefeller University shows th...
Science News

Structural study shows how bacteria select their most virulent proteins

Salmonella poisoning, dysentery, the plague, typhoid fever, and a number of other serious ailments are caused by a diverse group of bacterial pathogens that have one thing in common: They all use the same syringe-like system to infect their hosts. Known as a “type III secretion system,” this tra...
Science News

By targeting dendritic cells, HIV and malarial vaccines outperform competitors

Although DNA-based vaccines are often in the limelight, scientists at Rockefeller University are developing a completely different approach to inducing immunity, one that directs a vaccine straight to the immune cells of living animals and, eventually, humans. In two papers published this month i...
Awards and Honors

Rockefeller neurobiologist to receive Benjamin Franklin Medal

Rockefeller University’s Fernando Nottebohm will receive the 2006 Benjamin Franklin Medal in Life Science, The Franklin Institute in Philadelphia announced today. The medal recognizes Nottebohm’s discovery of neuronal replacement in the adult vertebrate brain and the elaboration of the mechanism...
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